Technology Process of 3,4-dihydroxy-2-iodobenzaldehyde
There total 2 articles about 3,4-dihydroxy-2-iodobenzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; aluminum (III) chloride;
In
dichloromethane;
at 0 ℃;
for 20.0833h;
Inert atmosphere;
Reflux;
DOI:10.1021/ol401197n
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridine; iodine; dihydrogen peroxide / water / 3 h / 30 °C / Inert atmosphere
1.2: 1.5 h / 20 - 40 °C / Inert atmosphere
2.1: pyridine; aluminum (III) chloride / dichloromethane / 20.08 h / 0 °C / Inert atmosphere; Reflux
With
pyridine; aluminum (III) chloride; dihydrogen peroxide; iodine;
In
dichloromethane; water;
DOI:10.1021/ol401197n
- Guidance literature:
-
3,4-dihydroxy-2-iodobenzaldehyde;
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
Inert atmosphere;
Isobutyl iodide;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 72h;
Inert atmosphere;
DOI:10.1021/ol401197n
