1229610-02-9

Basic information

• Product Name: 2-(2-methylphenyl)-4-phenyl-quinazoline
• Synonyms: 2-(2-methylphenyl)-4-phenyl-quinazoline
• CAS NO: 1229610-02-9
• Molecular Weight: 296.371
• Mol File: 1229610-02-9.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-(2-methylphenyl)-4-phenyl-quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methylphenyl)-4-phenyl-quinazoline(1229610-02-9)
• EPA Substance Registry System: 2-(2-methylphenyl)-4-phenyl-quinazoline(1229610-02-9)

Safety Data

• Hazardous Substances Data: 1229610-02-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 529-20-4 2-methylphenyl aldehyde 
• 100-46-9 benzylamine 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 304479-23-0 N-(2-cyanophenyl)-2-methylbenzamide 
• 98-80-6 phenylboronic acid 
• 51619-51-3 2-methyl-N-phenyl-benzimidoyl chloride 
• 7055-03-0 2-methyl-N-phenylbenzamide 
• 529-19-1 2-Methylbenzonitrile 
• 13141-38-3 2-phenylethynylaniline 
• 5589-60-6 2-[(2-methylbenzyl)amino]benzonitrile 
• 1885-29-6 anthranilic acid nitrile 
• 1448311-29-2 C₂₂H₁₈N₂O₃S 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

DDQ/TBHP-induced oxidative cyclization process: A metal-free approach for the synthesis of 2-phenylquinazolines

Various 2-phenylquinazoline derivatives were synthesized under metal-free conditions from readily available 2-aminophenyl ketones and benzylamines via condensation and oxidative cyclization using 2,3-dichloro-5,6-dicyano-1,4- benzoquinone (DDQ) as a versatile reagent. The reaction gave the corresponding 2-phenylquinazoline derivatives in good to excellent yields (up to 92%). Georg Thieme Verlag Stuttgart ? New York.

Copper-Catalyzed Three-Component Cascade Reaction of Benzaldehyde with Benzylamine and Hydroxylamine or Aniline: Synthesis of 1,2,4-Oxadiazoles and Quinazolines

The analogous three-component synthesis strategy for substituted 1,2,4-oxadiazole and quinazoline derivatives from readily available benzaldehyde, benzylamine and hydroxylamine or aniline has been developed. Both the cascade reaction sequences involves nucleophilic addition of C?N bond, introduction a halogen donor, nucleophilic substitution and Cu(II)-catalyzed aerobic oxidation. This synthesis methodology demonstrated good yields, broad substrate scope and oxygen as a green oxidant. Thus, this synthesis protocol provides strategies for the construction of substituted 1,2,4-oxadiazole and quinazolines from readily and simple starting materials. (Figure presented.).

Pd-Catalyzed tandem reaction of N-(2-cyanoaryl)benzamides with arylboronic acids: synthesis of quinazolines

The synthesis of 2,4-disubstituted quinazolines by a palladium-catalyzed reaction of arylboronic acids with N-(2-cyanoaryl)benzamides has been developed with moderate to excellent yields. The method shows good functional group tolerance. In particular, ha