1229611-67-9Relevant academic research and scientific papers
Design, synthesisand preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring
Guandalini,Balliu,Cellai,Martino,Nebbioso,Mercurio,Carafa,Bartolucci,Dei,Manetti,Teodori,Scapecchi,Altucci,Paoletti,Romanelli
, p. 56 - 68 (2013/10/01)
A series of new histone deacetylase inhibitors were designed and synthesized based on hybridization between SAHA or oxamflatin and 5-phenyl-1,4-benzodiazepines. The compounds were tested for their enzyme inhibitory activity on HeLa nuclear extracts, and o
