103421-61-0

Basic information

• Product Name: (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat
• Synonyms: (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat;2H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-1-methyl-5-phenyl-;3-AMINO-1-METHYL-5-PHENYL-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE;(Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamate;3-Amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• CAS NO: 103421-61-0
• Molecular Formula: C₁₆H₁₅N₃O
• Molecular Weight: 365.42562
• Mol File: 103421-61-0.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat(103421-61-0)
• EPA Substance Registry System: (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat(103421-61-0)

Safety Data

• Hazardous Substances Data: 103421-61-0(Hazardous Substances Data)

Usage

General Description

(Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat is a chemical compound that falls under the category of carbamates. It is a white to yellow crystalline solid with a molecular formula C20H24N2O3. (Z)-tert-butyl 1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamat is used in the field of medicinal chemistry for its potential pharmaceutical properties. It may have applications in the development of drugs targeting neurological disorders, as well as in the research of central nervous system (CNS) depressants. Additionally, it may also have potential applications in the development of psychoactive drugs. Further research and evaluation are necessary to fully understand the potential uses and effects of this chemical compound.

Upstream product

• 108895-97-2 2-α-(benzyloxycarbonyl)glycinyl)amino>benzophenone 
• 103-72-0 phenyl isothiocyanate 
• 103343-63-1 3(S)-(2(S)-amino-3-phenylpropanoylamino)-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 2898-08-0 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 14439-71-5 2'-benzoyl-2-bromo-acetanilide 
• 3034-65-9 1-methyl-2,3-dihydro-2-oxo-5-phenyl-1,4-benzodiazepine 
• 161365-74-8 benzyl N-[[(2-benzoylphenyl)carbamoyl](1H-1,2,3-benzotriazol-1-yl)methyl]carbamate 
• 108895-98-3 benzyl 2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamate 
• 103343-47-1 3-amino-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one 
• 74-88-4 methyl iodide 
• 157224-66-3 C₁₉H₁₈N₄O₃ 
• 103373-62-2 1,3-dihydro-1-methyl-3-oximido-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 106849-47-2 1,3-dihydro-1-methyl-5-phenyl-3(R,S)-<(benzyloxycarbonyl)-amino>-2H-1,4-benzodiazepin-2-one 

Downstream Products

• 134793-34-3 3(R,S)-(2,5-dihydroxy-benzoylamino)-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 118101-09-0 N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-3-methylphenyl urea 
• 134793-31-0 2-amino-3-(4-hydroxyphenyl)-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)propanamide 
• 170228-82-7 N-[(3R)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-2-bromoacetamide 

Relevant articles and documents

Discovery of clinical candidate BMS-906024: A potent pan-notch inhibitor for the treatment of leukemia and solid tumors

Structure-activity relationships in a series of (2-oxo-1,4-benzodiazepin-3-yl)-succinamides identified highly potent inhibitors of γ-secretase mediated signaling of Notch1/2/3/4 receptors. On the basis of its robust in vivo efficacy at tolerated doses in

5-PHENYL-LH-BENZ0 [E] [1, 4] DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS

Novel hydroxamate histone deacetylase inhibitors of formula (I) wherein X is C=O or CH2 used as antineoplastic agent.

Novel compounds useful for bradykinin B1 receptor antagonism

Disclosed are compounds that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the