123001-07-0Relevant articles and documents
Biocatalysis in Organic Synthesis. 9. Highly Enantioselective Kinetic Resolution of Secondary Alcohols Catalyzed by Acylase
Faraldos, Juan,Arroyo, Elisa,Herradón, Bernardo
, p. 367 - 370 (1997)
A new catalytic activity of the enzyme acylase I (AA-I) from Aspergillus species has been found. Although this enzyme had previously been used only in the hydrolysis of N-acylamino acids, we have found that it is a highly efficient catalyst for transesterifications using vinyl esters as acyl donors. The method has been applied to the kinetic resolution of a variety of secondary alcohols.
A new monooxygenase from: Herbaspirillum huttiense catalyzed highly enantioselective epoxidation of allylbenzenes and allylic alcohols
Lin, Hui,Tang, Yanhong,Dong, Shuang,Lang, Ruibo,Chen, Hongge
, p. 2145 - 2151 (2020/04/17)
Asymmetric epoxidation is a green route to enantiopure epoxides, but often suffers from low enantioselectivity toward unconjugated terminal alkenes. Mining of the NCBI non-redundant protein sequences with a reconstructed ancestral sequence based on six st
Iterative asymmetric allylic substitutions: Syn- and anti-1,2-diols through catalyst control
Park, Jin Kyoon,McQuade, D. Tyler
supporting information; experimental part, p. 2717 - 2721 (2012/04/17)
A copper-catalyzed asymmetric allylic boronation (AAB) gives access to syn- and anti-1,2-diols. The method facilitates an iterative strategy for the preparation of polyols (see scheme), such as the fully differentiated L-ribo-tetrol and protected D-arabin