123003-32-7Relevant academic research and scientific papers
Enantioselective reduction of aromatic and aliphatic ketones catalyzed by ruthenium complexes attached to β-cyclodextrin
Schlatter, Alain,Kundu, Mrinal K.,Woggon, Wolf-D.
, p. 6731 - 6734 (2004)
Water-soluble chiral Ru complexes with a β-cyclodextrin unit have been shown to catalyze the reduction of aliphatic ketones (see scheme) with up to 97% ee and in good to excellent yields in the presence of sodium formate. The β-cyclodextrin unit is an essential component of the catalyst. It contributes to the unprecedented levels of enantioselectivity observed through the preorganization of the substrates in the hydrophobic cavity.
Catalytic Asymmetric Synthesis of Optically Active Secondary Alcohols Deuterated on the Secondary Carbon by the Enantioselective Alkylation of Aldehydes
Soai, Kenso,Hirose, Yuji,Sakata, Shuichi
, p. 1734 - 1735 (2007/10/02)
Optically active secondary alcohols deuterated on the secondary carbon were obtained in high enantiomeric excesses from the enantioselective addition of dialkylzincs to aldehyde-formyl-d's using chiral catalysts.
