123003-88-3

Upstream product

• 79-20-9 acetic acid methyl ester 
• 122673-11-4 1-(4-methoxyphenyl)-4-(α-methylstyryl)azetidin-2-one 
• 121766-45-8 (3S,4R)-1-(4-Methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-3-(1-nitro-ethyl)-azetidin-2-one 
• 121766-44-7 1-(4-Methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-3-[1-nitro-eth-(Z)-ylidene]-azetidin-2-one 
• 121766-42-5 (3S,4R)-3-Hydroxy-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 130194-62-6 1-(4-Methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidine-2,3-dione 
• 121766-44-7 4-(α-methylstyryl)-1-(4-methoxyphenyl)-3-(1-nitroethylidene)azetidin-2-one 
• 121766-42-5 3-Hydroxy-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 94612-37-0 1-(4-methoxyphenyl)-4-(3-phenylprop-2-en-2-yl)-2,3-azetidinedione 
• 100239-15-4 (E)-4-methoxy-N-((E)-2-methyl-3-phenylallylidene)aniline 
• 100239-22-3 trans-3-(1-hydroxyethyl)-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 121766-45-8 cis,anti-4-(α-methylstyryl)-1-(4-methoxyphenyl)-3-(1-nitroethyl)azetidin-2-one 

Downstream Products

• 122673-15-8 trans-3-(1-hydroxyethyl)-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 122673-13-6 trans-3-(1-hydroxyethyl)-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 100239-22-3 3-(1-Hydroxy-ethyl)-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 

Relevant academic research and scientific papers

Tributyltin Hydride Addition to Nitroalkenes: A Convenient Procedure for the Conversion of Nitroalkenes into Nitroalkanes and Carbonyl Compounds

A new procedure for the reduction of nitroalkenes by using n-tributyltin hydride as reducing agent is desribed.The reaction proceeds under almost neutral conditions and works well even in the presence of other reduceable functionalities.Hydrolysis and Nef reaction of the resulting nitronates furnished nitroalkanes and carbonyl compounds respectively in high yields.Application of this methodology to the preparation of β-lactam building blocks is also made.

The Reformatsky Type Reaction of Gilman and Speeter in the Preparation of Valuable β-Lactams in Carbapenem Synthesis: Scope and Synthetic Utility

The preparation of apppropriately substituted 3-alkyl β-lactams from the Reformatsky type reaction of Gilman and Speeter is described.Treatment of Schiff bases derived from α-methylcinnamaldehyde and amines with ethyl α-bromobutyrate or ethyl α-bromoisova

SYNTHETIC UTILITY OF AZETIDINE-2,3-DIONES: A NEW APPROACH TO 3-HYDROXYETHYL-β-LACTAMS AND α-AMINOACID DERIVATIVES

Baeyer-Villiger oxidation of azetidine-2,3-diones provides a new route to α-aminoacid-N-carboxyanhydrides.Conversion of azetidine-2,3-diones into 3-acetyl-β-lactams is also described.