123017-04-9

Upstream product

• 134340-00-4 bis(trimethylsilyl)methylamine 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 134339-88-1 (2R,3R)-3-Phenyl-2-trimethylsilanyl-3,4-dihydro-2H-pyrrole 
• 134339-84-7 (2R,3R)-3-Phenyl-1,2-bis-trimethylsilanyl-2,3-dihydro-1H-pyrrole 
• 198021-49-7 (2S,3S)-1-(Bis-trimethylsilanyl-methyl)-4-oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-azetidine-2-carboxylic acid 
• 187161-86-0 (3S)-1-[bis(trimethylsilyl)methyl]-3-[(4S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]azetidin-2-one 
• 198022-09-2 (S)-3-[(3S,4R)-1-(Bis-trimethylsilanyl-methyl)-2-oxo-4-((E)-styryl)-azetidin-3-yl]-4-phenyl-oxazolidin-2-one 
• 134339-93-8 (2R,3R)-3-Phenyl-2-trimethylsilanyl-pyrrolidine 

Relevant academic research and scientific papers

A contribution to the asymmetric synthesis of 3-amine β-lactams: The diastereoselective [2+2] cycloaddition reaction of chiral aminoketene equivalents with enolizable aldehyde-derived/mines

N-[Bis(trimethylsilyl)methyl]imines 9 show unique chemical properties when compared with conventional imines. Their reaction with optically pure aminoketenes derived from dehydrochlorination of 14 and 15 affords the corresponding 3-amino-4-alkyl-β-lactams