123020-21-3

Basic information

• Product Name: 1H-Indole-3-carboxylic acid, 7-iodo-, Methyl ester
• Synonyms: 1H-Indole-3-carboxylic acid, 7-iodo-, Methyl ester;methyl 7-iodo-1H-indole-3-carboxylate;7-Iodo-1H-indole-3-Carbocylic acid methyl ester
• CAS NO: 123020-21-3
• Molecular Formula: C₁₀H₈INO₂
• Molecular Weight: 301.08049
• Mol File: 123020-21-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole-3-carboxylic acid, 7-iodo-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-carboxylic acid, 7-iodo-, Methyl ester(123020-21-3)
• EPA Substance Registry System: 1H-Indole-3-carboxylic acid, 7-iodo-, Methyl ester(123020-21-3)

Safety Data

• Hazardous Substances Data: 123020-21-3(Hazardous Substances Data)

Usage

Structure

Methyl ester derivative of 7-iodo-1H-indole-3-carboxylic acid

Type of compound

Organic compound

Contains

Indole ring, carboxylic acid functional group, and an iodine atom at the 7th position

Usage

Organic synthesis for the preparation of pharmaceuticals and agrochemicals

Biological activities

Potential anti-inflammatory and anti-cancer properties

Precautions

Potential hazardous properties, should be handled with proper care and by trained professionals.

Upstream product

• 942-24-5 3-methoxycarbonylindole 
• 89976-15-8 7-iodo-1H-indole 
• 67-56-1 methanol 
• 123020-22-4 7-iodo-1H-indole-3-carbaldehyde 

Downstream Products

• 473919-00-5 1'-(2-benzyloxy-benzoyl)-3-formyl-1'H-[4,7']biindolyl-1,3'-dicarboxylic acid 1-tert-butyl ester 3'-methyl ester 
• 473918-99-9 1-(2-benzyloxy-benzoyl)-7-iodo-1H-indole-3-carboxylic acid methyl ester 

Relevant articles and documents

Diazonamide synthesis studies: Use of negishi coupling to fashion diazonamide-related biaryls with defined axial chirality

(matrix presented) The syntheses of a bis indole and an indole salicylate with the required axial chirality for diazonamide A are reported. Atropselectivity in these biaryl systems is enforced by an sp3 stereogenic center in a lactone tether in

Syntheses of wasabi phytoalexin (methyl 1-methoxyindole-3-carboxylate) and its 5-iodo derivative, and their nucleophilic substitution reactions

A simple synthetic method for methyl 1-methoxyindole-3-carboxylate, a phytoalexin isolated from Wasabia japonica, syn. Eutrema wasabi, and its 5-iodo derivative is reported. They underwent nucleophilic substitution reactions selectively at the 2-position.