123060-91-3

Basic information

• Product Name: ethyl 3-(m-methylphenylethyl)-2-methyl-4-oxocyclohex-2-encarboxylate
• Synonyms: ethyl 3-(m-methylphenylethyl)-2-methyl-4-oxocyclohex-2-encarboxylate
• CAS NO: 123060-91-3
• Molecular Weight: 300.398
• Mol File: 123060-91-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 3-(m-methylphenylethyl)-2-methyl-4-oxocyclohex-2-encarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(m-methylphenylethyl)-2-methyl-4-oxocyclohex-2-encarboxylate(123060-91-3)
• EPA Substance Registry System: ethyl 3-(m-methylphenylethyl)-2-methyl-4-oxocyclohex-2-encarboxylate(123060-91-3)

Safety Data

• Hazardous Substances Data: 123060-91-3(Hazardous Substances Data)

Upstream product

• 487-51-4 4-carbethoxy-3-methyl-2-cyclohexen-1-one 
• 16799-08-9 1-(2-bromoethyl)-3-methylbenzene 

Downstream Products

• 123060-93-5 2-(m-methylphenylethyl)-3,3-dimethylcyclohexan-1-one 
• 123060-98-0 2-(2-m-methylphenylethyl)-1,3,3-trimethylcyclohexanol 
• 123060-92-4 3-methyl-2-[2-(3-methylphenyl)ethyl]cyclohex-2-en-1-one 

Relevant articles and documents

INFLUENCE OF METHOXY- AND METHYL-AROMATIC SUBSTITUENS ON STEREOCHEMISTRY OF THE PRODUCTS IN THE ACID-CATALIZED CYCLIZATION OF 2-(2-ARYLETHYL)-1,3,3-TRIMETHYLCYCLOHEXANOLS: STEREOCONTROLLED TOTAL SYNTHESIS OF (+/-)- NIMBIDIOL AND (+/-)-NIMBIOL

The distributions of the trans- and the cis-podocarpatrienes (5c-g) and (6c-g) in the cyclialkylation reaction of the easily accesible cyclohexanols (4c-g) under a mild condition have been investigated.The cyclohexanol precursors having unactivated aromatic ring proceeds with high stereoselectivity leading to the respective trans-products, while the substrates with an electron donating methoxy or a methyl substituent with respect to the site of electrophilic attack result in the corresponding cis- and the trans-product mixtures.Consistent mechanisms for these stereochemical results have been advanced.Based on these results simple synthesis of the modified diterpenes (+/-)-nimbidiol (7) and (+/-)-nimbiolmethylether (18) have been realized.