123088-32-4

Upstream product

• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 79881-33-7 2,6-dichloro-4'-biphenylol 
• 18855-13-5 Biphenyl-3,4'-diol 
• 319014-58-9 4-[2-(trifluoromethyl)phenyl]phenol 
• 19812-93-2 4-Cyano-4'-hydroxybiphenyl 
• 10355-13-2 4-hydroxy-4'-trifluoromethylbiphenyl 
• 22510-31-2 4-(4'-fluoro-3'-chloro-phenyl)phenol 
• 634192-41-9 4'-fluoro-3'-trifluoromethyl-biphenyl-4-ol 

Relevant academic research and scientific papers

ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template.

The synthesis and structure-activity relationships of a series of simple biphenyls is described. Optimization of the 4-hydroxy-biphenyl template led to compounds with ERbeta selectivity on the order of 20-70-fold.