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Usage

Uses

Used in Organic Electronic Materials:
[1,1'-biphenyl]-3,4'-diol is used as a component in organic electronic materials due to its unique structure and properties, which contribute to the performance and functionality of these materials.
Used in Synthesis of Biologically Active Compounds:
As a precursor, [1,1'-biphenyl]-3,4'-diol is utilized in the synthesis of various biologically active compounds, leveraging its chemical properties to create molecules with potential therapeutic effects.
Used in Antioxidant Applications:
[1,1'-biphenyl]-3,4'-diol is used as an antioxidant to combat oxidative stress, potentially playing a role in the treatment of diseases associated with oxidative stress due to its ability to neutralize free radicals.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, [1,1'-biphenyl]-3,4'-diol serves as a building block in the synthesis of organic compounds, which can be further developed into drugs with specific therapeutic applications.
Used in Agrochemical Applications:
Similarly, in agrochemistry, [1,1'-biphenyl]-3,4'-diol is used as a starting material for the synthesis of compounds that can be employed in the development of pesticides or other agrochemical products.
Used in Materials Science Applications:
[1,1'-biphenyl]-3,4'-diol is also utilized in materials science, where it contributes to the development of new materials with specialized properties, such as those used in coatings, adhesives, or other industrial materials.

Upstream product

• 591-20-8 3-Bromophenol 
• 123088-32-4 4-tert-butyl-dimethylsilyloxyphenylboronic acid anhydride 
• 84591-12-8 1-methoxy-3-(4-methoxyphenyl)benzene 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 626-02-8 3-Iodophenol 
• 106-41-2 4-bromo-phenol 
• 87199-18-6 3-hydroxyphenylboronic acid 
• 540-38-5 p-Iodophenol 
• 29097-92-5 3-(4-hydroxyphenyl)-2-cyclohexen-1-one 
• 36603-49-3 4-(tetrahydropyran-2'-yloxy)-1-bromobenzene 
• 1287777-07-4 (biphenyl-3,4'-diyloxy)bis(tetrahydro-2H-pyran) 
• 121554-09-4 4-(n-octyloxy)phenylboronic acid 
• 2398-37-0 3-methoxyphenyl bromide 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 

Downstream Products

• 724449-06-3 3,4'-biphenyl bis-4-(tetrahydropyran-2'-yloxy)benzoic acid 
• 851379-10-7 3,4'-bis{4-[4-(10-undec-1-yloxy)benzoyloxy]benzoyloxy}biphenyl 

Relevant academic research and scientific papers

Suzuki-Miyaura coupling of halophenols and phenol boronic acids: Systematic investigation of positional isomer effects and conclusions for the synthesis of phytoalexins from pyrinae

The Suzuki-Miyaura couplings of o-, m-, and p-halophenols with o-, m-, and p-phenol boronic acids were investigated for all combinations under standardized conditions, using Pd/C as a heterogeneous catalyst and water as a solvent. In the case of iodophenols, conventional heating was used, while for bromophenols significantly better results could be obtained using microwave irradiation. This systematic study revealed that 2,4′-biphenol is particularly difficult to access, irrespective of the starting materials used, but that these difficulties can be overcome by using different additives. The conclusions drawn from this investigation allowed us to identify conditions for the protecting group-free or minimized total synthesis of biaryl-type phytoalexins. These compounds possess antibacterial activity and are produced by fruit trees as a response to microbial infection.

A modulated helical nanofilament phase

A new liquid crystal phase, denoted modulated helical nanofilament (HNF(mod)), is formed from a very simple class of biphenyl carboxylates lacking the benzylidene aniline moieties typically found in HNF mesogens. The HNF(mod) phase represents a novel kind of nanoparticle possessing stacked aromatic rings, with potential applications in organic electronics. Copyright

Polymerizable compound and liquid crystal composition including it

Provided is a polymerizable compound with large solubility in a liquid crystal composition and high reactivity irradiated by ultraviolet in the longer wavelength range. Provided is a liquid crystal composition that satisfies at least one of characteristics such as high maximum temperature of a nematic phase, low minimum temperature of a nematic phase, small viscosity, suitable optical anisotropy, large negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light and high stability to heat, or that is suitably balanced between at least two of the characteristics. Provided is the polymerizable compound wherein at least one of a 1,3-phenylene structure and a 2,7-fluorenediyl structure is introduced to the polymerizable compound to give stable displays by forming a polymer with a high degree of polymerization in a PSA device production process using longer wavelengths, the liquid crystal composition includes the compound, and the liquid crystal display device contains the composition.

Aerobic oxidative heck/dehydrogenation reactions of cyclohexenones: Efficient access to meta-substituted phenols

Jockeying for the (meta)position: A new dicationic palladium(II) catalyst, employing a 6,6′-dimethyl-2,2′-bipyridine ligand, promotes both the aerobic oxidative Heck coupling and dehydrogenation reactions of cyclohexenones. These reactions may be combined in a one-pot sequence to enable the straightforward synthesis of meta-substituted phenols (see scheme). Copyright

METHOD OF PRODUCING BIPHENOLIC COMPOUND, NOVEL BIPHENYL COMPOUND AND SYNTHESIS METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING PARKINSON'S DISEASE

A method of producing honokiol and analogues thereof, and novel intermediates prepared by virtue thereof are disclosed herein. A pharmaceutical composition for treating Parkinson's disease, which contains honokiol and/or the analogues thereof, is also disclosed herein.

An expedient synthesis of honokiol and its analogues as potential neuropreventive agents

An efficient synthesis of honokiol with Suzuki-Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.

Synthesis and characterization of achiral bent-core liquid crystalline molecules containing salicylaldimine-based with a wide temperature range of SmCP phase

The design and synthesis of a series bent-core materials base on a 3,4'-biphenyldiol central core containing salicylaldimine-based and two terminal tetradecyloxy tails are reported. In addition, the effects of lateral substituents (R = F and Cl) at the biphenyl core into 3'-position are examined. These substituents have a strong influence in reducing the clearing temperatures and increasing temperature range of SmCP phase. Upon cooling process the isotropic liquid, compound SB-Cl exhibits the lowest clearing transition temperature of 180 oC and the widest SmCP phase range of 129 °C. The mesophase behaviour were investigated by polarizing optical microscopy (POM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), and electro-optical (EO) measurements in the mesophase temperature range.

Novel photochromism of differently-linked bis-benzopyrans

The unique photochromic bis-chromene 5 incorporates the structural attributes of both 3 and 4. UV-vis irradiation of 5 leads to a dark brown colour, which is formed by mixing the purple and red colours observed for the photolysates of 3 and 4, respectively. The Royal Society of Chemistry.

ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template.

The synthesis and structure-activity relationships of a series of simple biphenyls is described. Optimization of the 4-hydroxy-biphenyl template led to compounds with ERbeta selectivity on the order of 20-70-fold.

Molecular design of nonchiral bent-core liquid crystals with antiferroelectric properties

Novel bent-core (banana-shaped) liquid crystals without Schiff-base units have been synthesized and investigated by polarized light optical microscopy, differential scanning calorimetry, X-ray scattering, and electrooptical investigations. These molecules are 4-(4- alkylbenzoyloxy)benzoates and 4-(4-alkoxybenzoyloxy)benzoates of resorcinol, 3,4'-dihydroxybiphenyl, and 4,4'-dihydroxy- 1,1':3', 1'-terphenyl. Three different mesophases were found depending on the molecular structure and the length of the terminal alkyl chains: a rectangular columnar phase, a highly ordered low-temperature mesophase, and an antiferroelectric switchable fluid smectic mesophase designated as SmCP(A). The influence of the molecular structure on the occurrence of the SmCP(A) phase was investigated. The spontaneous polarization of these molecules is quite high (P(s) = 500700 nC cm-2) and specially those molecules with long alkyl chains and short bent- core structures have low melting points and broad regions of this switchable mesophase. Furthermore, first examples of antiferroelectric switchable bent- core molecules with semifluorinated terminal chains will be described.