1232365-46-6

Basic information

• Product Name: 1-(ethoxycarbonyl)-3-fluorocyclobutanecarboxylic acid
• CAS NO: 1232365-46-6
• Molecular Weight: 190.171
• Mol File: 1232365-46-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(ethoxycarbonyl)-3-fluorocyclobutanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(ethoxycarbonyl)-3-fluorocyclobutanecarboxylic acid(1232365-46-6)
• EPA Substance Registry System: 1-(ethoxycarbonyl)-3-fluorocyclobutanecarboxylic acid(1232365-46-6)

Safety Data

• Hazardous Substances Data: 1232365-46-6(Hazardous Substances Data)

Upstream product

• 123812-76-0 diethyl 3-fluorocyclobutane-1,1-dicarboxylate 
• 105-53-3 diethyl malonate 
• 99974-66-0 diethyl 3-hydroxycyclobutane-1,1-dicarboxylate 
• 54166-15-3 diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate 

Relevant articles and documents

CYSTEINE PROTEASE INHIBITORS

Compounds of the formula (I) wherein One of A1 and A2 is N-CH3 and the other is CH; R1 is C1-C6alkyl, C1-C6haloalkyl, C3-C6cycloalkyl or oxetan-3-yl, wherein C3-C6cycloalkyl is optionally substituted with one, two or three fluoro or with CF3; R2a and R2b are independently selected from H, halo, C1-C4alkyl, C1-C4haloalkyl and C1- C4alkoxy; R3 is CH3 or F; n is 1, 2, 3 or 4; or a pharmaceutically acceptable salt, hydrate or N-oxide thereof for the use in the prophylaxis and/or treatment of a disorder characterised by inappropriate expression or activation of cathepsin S.

CYSTEINE PROTEASE INHIBITORS

Compounds of Formula (II) wherein R1a is H; and R1b is C1-C6alkyl, Carbocyclyl or Het; or R1a and R1b together define a saturated cyclic amine with 3-6 ring atoms; R2a and R

CYSTEINE PROTEASE INHIBITORS

Compounds of the formula I wherein R1a is H; and R1b is C1-C6 alkyl, Carbocyclyl or Het; or R1a and R1b together define a saturated cyclic amine with 3-6 ring atoms; R2a and Rsu