123331-31-7

Basic information

• Product Name: 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one
• Synonyms: 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one
• CAS NO: 123331-31-7
• Molecular Weight: 216.239
• Mol File: 123331-31-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one(123331-31-7)
• EPA Substance Registry System: 1-(1H-imidazol-1-yl)-2-(4-methoxyphenyl)ethan-1-one(123331-31-7)

Safety Data

• Hazardous Substances Data: 123331-31-7(Hazardous Substances Data)

Upstream product

• 104-01-8 4-Methoxyphenylacetic acid 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 862281-52-5 1-(4-methoxy-phenyl)-3-nitro-acetone 
• 26087-09-2 3-(4-methoxyphenyl)-4-methyl-2H-chromen-2-one 
• 112768-11-3 6-bromo-3-(4-methoxyphenyl)-2H-chromen-2-one 
• 263364-71-2 6-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one 
• 23000-33-1 3-(4-methoxyphenyl)coumarin 
• 2594-06-1 2-(4-methoxyphenyl)acetohydroxamic acid 
• 99931-94-9 2-(4-methoxyphenyl)-1-morpholinoethan-1-one 
• 119784-75-7 2-(4-methoxyphenyl)-1-(piperazin-1-yl)ethanone 
• 131471-29-9 6-Hydroxy-5-(4-methoxy-phenyl)-8H-3,7,8,9b-tetraaza-cyclopenta[a]naphthalen-9-one 
• 123331-43-1 Dimethyl 7-(4-Methoxyphenyl)imidazo<1,2-a>pyridine-5,6-dicarboxylate 
• 120049-02-7 dimethyl (imidazol-1-yl)fumarate 

Relevant articles and documents

Green Synthesis of Spiropyranone 3-Aryl-4-Methylcoumarin Derivatives using Carbonyldiimidazole

A series of spiropyranone 3-aryl-4-methylcoumarin derivatives have been synthesized from monospiro-2-hydroxy acetophenone in a novel and efficient green method using imidazolyl intermediates and inorganic base. Imidazolyl intermediates were in turn genera

Facile one-pot synthetic access to libraries of diversely substituted 3-aryl (Alkyl)-coumarins using ionic liquid (IL) or conventional base/solvent, and an IL-mediated approach to novel coumarin-bearing diaryl-ethynes

The in-situ formed carbonylimidazole derivatives of Ar(alkyl)-CH2COOH react at r.t. with substituted salicylaldehydes in [BMIM][PF6] or [BMIM][BF4] as solvent, and [PAIM][NTf2] as basic-IL, to produce libraries of 3-aryl(alkyl)coumarins. Whereas these reactions can also be performed with similar efficiency in THF by employing DBU, the IL approach offers easier work-up and recycling of the IL solvent. An IL-mediated approach to the synthesis of novel coumarin-bearing diaryl-ethynes by the Sonogshira reaction is also reported, and the potential for recycling/reuse of the IL solvent is shown.

New bioactive triaryl triglyceride esters: Synthesis, characterization and biological activities

Four new bioactive aryl triester derivatives of glycerol and benzoic acids were synthesized. The synthetic compounds were studied for their antimicrobial and urease inhibition activities. Esterification was carried out by using carbonyldiimidazole to enhance the acyl elimination addition reaction with benzoic acid derivatives. The structure of triglycerides were studied by EI-MS,1H,13C-NMR, FT-IR and elemental analysis. All synthetic compounds showed urease inhibition activity with highest value of IC50 value 22.4 ± 0.45 μM which is nearest to standard thiourea IC50 value (21.6 ± 0.12 μM). Except compound (3d), all other compounds exhibited antimicrobial activity against Streptococcus pneumoniae, Staphylococcus epidermidis, Bacillus pumilus, Escherichia coli, Pseudomonas aeruginosa and Candida albican.