1233335-41-5

Upstream product

• 1233335-28-8 (4R, 6R, 7S)-4,7-di(tert-butyldimethylsilyloxy)-2-iodo-4,5,6,7-tetrahydrobenzo[b]thiophen-4,6-carbolactone 
• 98-80-6 phenylboronic acid 
• 185810-83-7 (1S,3R,4R,5R)-3-benzyloxy-1,4-dihydroxycyclohexane-1,5-carbolactone 
• 862791-12-6 (1R,4S,5R)-1,4-bis(tert-butyldimethylsilyloxy)-3-oxocyclohexane-1,5-carbolactone 
• 1206715-87-8 (1R, 2R, 4S, 5R)-2-allyl-1,4-di(tert-butyldimethylsilyloxy)-3-oxocyclohexan-1,5-carbolactone 
• 862791-08-0 (1S,3R,4R,5R)-3-benzyloxy-1,4-bis(tert-butyldimethylsilyloxy)cyclohexane-1,5-carbolactone 
• 862791-10-4 (1S,3R,4R,5R)-1,4-bis(tert-butyldimethylsilyloxy)-3-hydroxycyclohexane-1,5-carbolactone 
• 1206715-85-6 (1S, 2R, 4S, 5R)-2-bromo-1,4-di(tert-butyldimethylsilyloxy)-3-oxocyclohexan-1,5-carbolactone 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 1233335-20-0 (4R, 6R, 7S)-4,7-di(tert-butyldimethylsilyloxy)-4,5,6,7-tetrahydrobenzo[b]thiophen-4,6-carbolactone 

Downstream Products

• 1233335-43-7 (4R,6R,7S)-4,7-dihydroxy-2-phenyl-4,5,6,7-tetrahydrobenzo[b]thiophene-4,6-carbolactone 

Relevant academic research and scientific papers

COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME

The present invention is directed to a compound of formula (I), its diastereoisomers, its enantiomers or its pharmaceutically acceptable salts or solvates, formula (I), to procedures of obtaining the same, to intermediates thereof, and use as competitive inhibitors of the third enzyme of the shikimic acid pathway, the type II dehydroquinase.

Competitive inhibitors of type ii dehydroquinase enzyme

The present invention is directed to a compound of formula I, its diastcrcoisomcrs, its enantiomers or its pharmaceutically acceptable salts or solvates, to procedures of obtaining the same, to intermediates thereof, and use as competitive inhibitors of