185810-83-7Relevant academic research and scientific papers
Design and synthesis of mimics of S-Adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases
Hanessian, Stephen,Sgarbi, Paulo W.M.
, p. 433 - 437 (2007/10/03)
A series of indanotriazine C-ribosides were prepared as SAH mimics, and tested for their ability to inhibit erythromycin resistance methylases Erm AM and Erm C'. A carbocyclic analogue derived from quinic acid was also synthesized and tested. (C) 2000 Elsevier Science Ltd. All rights reserved.
Total synthesis of (-)-reserpine using the chiron approach
Hanessian, Stephen,Pan, Jingwen,Carnell, Andrew,Bouchard, Herve,Lesage, Luc
, p. 465 - 473 (2007/10/03)
A highly stereocontrolled synthesis of ring D/E precursor to reserpine has been developed starting from (-)-quinic acid as a chiral template. The total synthesis of (-)-reserpine is described through the cyclization of an immonium lactam intermediate.
