123343-99-7

Usage

Uses

Used in Medicinal Chemistry:
N-(2-Fluoro-5-nitrophenyl)methanesulfonamide is used as a building block in the synthesis of various biologically active molecules and potential drug candidates. Its unique structure and properties make it a valuable component in the development of new pharmaceuticals.
Used in Pharmaceutical Development:
N-(2-Fluoro-5-nitrophenyl)methanesulfonamide is used as a key intermediate in the development of new pharmaceuticals, particularly those targeting specific biological pathways or diseases.
Used in Antimicrobial Applications:
N-(2-Fluoro-5-nitrophenyl)methanesulfonamide exhibits antimicrobial properties, making it a potential candidate for the development of new antibiotics. Its ability to target and inhibit the growth of bacteria can contribute to the creation of novel treatments for bacterial infections.
Used in Antifungal Applications:
N-(2-Fluoro-5-nitrophenyl)methanesulfonamide also demonstrates antifungal properties, positioning it as a potential candidate for the development of new antifungal agents. Its effectiveness against fungi can lead to the creation of treatments for various fungal infections and diseases.

Upstream product

• 369-36-8 6-fluoro-3-nitroaniline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 51765-49-2 N-(5-nitro-2-phenoxyphenyl)methanesulfonamide 
• 123343-90-8 N-(5-amino-2-fluorophenyl)methanesulfonamide 
• 150779-46-7 N-(2-cyclohexyloxy-5-nitrophenyl)methanesulfonamide 
• 253339-77-4 2'-[2-(isopropylamino)ethoxy]-5'-nitromethanesulfonanilide 
• 157921-53-4 N-(2-Fluoro-5-nitro-phenyl)-N-methyl-methanesulfonamide 

Relevant academic research and scientific papers

AMINOPYRAZOLE DERIVATIVES

An objective of the present invention is to provide low-molecular-weight compounds that can inhibit Src family kinases. The present invention relates to compounds represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ar1 is optionally substituted C6-10 arylene or 5- to 10-membered heteroarylene, and Ar2 is optionally substituted C6-10 aryl or 5- to 10-membered heteroaryl. R1 and R2 are defined as described in the specification.

Anilide derivatives and antiarrhythmic agents containing the same

Preparation of antiarrhythmic agents containing novel anilide derivatives represented by the following formula as active ingredient provides a new type of antiarrhythmic agent of highly safe and effective, without effects on cardiac function.

5-aminoacetylaminosulfonanilide compounds

The present compounds represented by the formula: STR1 (wherein R1 is a phenyl group, a halophenyl group or a cycloalkyl group having 3 to 8 carbon atoms, R2 is a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, R3 is a hydrogen atom, an alkyl group having 1 to 7 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, an alkenyl group having 3 to 5 carbon atoms or a benzyl group, or R2 and R3 are bonded together to form a 5- to 7-membered heterocycle) and salts thereof have potent anti-inflammatory, antipyretic, analgesic and anti-allergic actions with less side effects such as gastrointestinal disorders and with such a high safety as to permit long-term administration.

5-amino-2-phenoxysulfonanilide compound

To provide an excellent compound having anti-inflammatory, antipyretic, analgesic and antirheumatic actions. A 5-amino-2-phenoxysulfonanilide compound represented by the formula: STR1 and the salts thereof have potent anti-inflammatory, antipyretic, analg

5-aminosulfonanilide compounds

5-Aminosulfonanilide compounds represented by the formula: STR1 (wherein R is a hydrogen atom, a formyl group, an acetyl group, a propionyl group, an n-butyryl group, an n-valeryl group, an ethoxyoxalyl group, an n-propoxyoxalyl group, a methoxycarbonylac

SYNTHESIS OF 2,1-BENZISOTHIAZOLINE 2,2-DIOXIDE DERIVATIVES

Base-induced (NaOH/DMSO) intramolecular SNAr of fluorine in methanesulfonanilide 1 derivatives leads to 6-nitro-2,1-benzisothiazoline derivatives 2. meta-Nitro methanesulfonanilides 3 in the presence of tert-BuOK in DMF were transformed into 4-