157921-53-4Relevant articles and documents
Selective sodium channel regulator as well as preparation and application thereof
-
, (2021/02/10)
The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.
SYNTHESIS OF 2,1-BENZISOTHIAZOLINE 2,2-DIOXIDE DERIVATIVES
Wojciechowski, K.
, p. 1121 - 1124 (2007/10/02)
Base-induced (NaOH/DMSO) intramolecular SNAr of fluorine in methanesulfonanilide 1 derivatives leads to 6-nitro-2,1-benzisothiazoline derivatives 2. meta-Nitro methanesulfonanilides 3 in the presence of tert-BuOK in DMF were transformed into 4-