1233485-16-9

Basic information

• Product Name: tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate
• CAS NO: 1233485-16-9
• Molecular Weight: 320.339
• Mol File: 1233485-16-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate(1233485-16-9)
• EPA Substance Registry System: tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate(1233485-16-9)

Safety Data

• Hazardous Substances Data: 1233485-16-9(Hazardous Substances Data)

Upstream product

• 1033225-43-2 2,6-difluoro-N-(2-nitrophenyl)aniline 
• 1033225-44-3 N-(2,6-difluorophenyl)benzene-1,2-diamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 5509-65-9 2,6-difluoroaniline 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 1033225-45-4 1-(2,6-difluorophenyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide 
• 1233485-18-1 1-(tert-butyloxycarbonyl)-3-(2,6-difluorophenyl)-1,3-dihydrobenzothiadiazole-S,S-dioxide 
• 1033226-24-2 tert-butyl 4-(2-(3-(2,6-difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl)ethyl)piperazine-1-carboxylate 
• 1033221-94-1 1-(2,6-difluorophenyl)-1,3-dihydro-3-[2-(1-piperazinyl)ethyl]benzothiadiazole-S,S-dioxide 
• 1233485-20-5 1-(2,6-difluorophenyl)-1,3-dihydro-3-[2-(1-piperazinyl)ethyl]benzothiadiazole-S,S-dioxide succinate 
• 1233485-17-0 1-(tert-butyloxycarbonyl)-3-(2,6-difluorophenyl)-1,3-dihydrobenzothiadiazole-S-oxide 

Relevant articles and documents

Development of a pilot-plant-scale synthesis of an alkylated dihydrobenzothiadiazole S, S-dioxide: Incorporation of a late-stage mitsunobu reaction

The process used to prepare a functionalized dihydrobenzothiadiazole S,S-dioxide on a pilot plant scale is described. Key changes to the original synthesis included: modifying SNAr reaction conditions between a substituted aniline and 2-fluoron