1234177-52-6Relevant articles and documents
Magnetically recyclable CuFe2O4 catalyst for efficient synthesis of bis(indolyl)methanes using indoles and alcohols under mild condition
Bui, Hoang Yen,Dang, Tuan Thanh,Ha, Minh-Tuan,Hung, Tran Quang,Nguyen, Ngoc-Khanh,Nguyen, Van Tuyen,Tran, Bich Ngoc,Trinh, Quang Thang,Vu, Xuan Hoan
, (2021)
Bis(3-indolyl)methanes (BIM) are highly valuable and appear in the core structure of many natural products and pharmacologically active compounds (anticancer, anti-inflammatory, antiobesity, antimetastatic, antimicrobial, etc.). Herein, we have disclosed
Graphene oxide: An efficient recyclable solid acid for the synthesis of bis(indolyl)methanes from aldehydes and indoles in water
Wang, Yihong,Sang, Rui,Zheng, Yang,Guo, Li,Guan, Mei,Wu, Yong
, p. 138 - 142 (2016/11/19)
An efficient synthesis of bis(indolyl)methanes from aldehydes with indoles through graphene oxide -catalyzed Friedel-Crafts alkylation is developed. The reaction proceeds in water by using graphene oxide as the single catalyst to provide the desired products in good to excellent yields. Also, this methodology has a broad substrate scope, and is environment friendly and cost economic.
CuBr-catalyzed selective oxidation of N-azomethine: Highly efficient synthesis of methine-bridged bis-indole compounds
Yang, Jianguo,Wang, Zhijing,Pan, Fuyou,Li, Yongmin,Bao, Weiliang
experimental part, p. 2975 - 2978 (2010/09/06)
An efficient CuBr catalyzed cleavage of C-N bonds in the oxidative cross-dehydrogenative-coupling (CDC) of N-benzyl amines with indoles mediated by tert-butyl hydroperoxide (TBHP) was reported. A series of methine-bridged bis-indole derivatives were successfully synthesized under the optimized reaction conditions.
