1234178-32-5Relevant academic research and scientific papers
Sonogashira couplings of halo- and epoxy-halo-exo-glycals: Concise entry to carbohydrate-derived enynes
Gomez, Ana M.,Barrio, Aitor,Pedregosa, Ana,Uriel, Clara,Valverde, Serafin,Cristobal Lopez
, p. 2910 - 2920 (2010)
Furanose- and pyranose-derived mono- and dihalo-exo-glycals undergo Sonogashira coupling reactions in the presence of Pd catalysts to give carbohydrate-derived enynes in a completely stereoselective manner. On the other hand, a furanose-derived 2, 3-anhydrohalo-exo-glycal, available from D-mannose in five steps, undergoes Pd0-catalyzed Sonogashira coupling, leading to 2-deoxyenynes.
