123439-72-5

Upstream product

• 67-56-1 methanol 
• 123439-71-4 Imidazole-1-carbothioic acid O-[(2R,3S,5R)-5-(2-amino-4-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-yl] ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 123439-70-3 2-amino-4-chloro-7-<2-deoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-β-D-erythro-pentofuranosyl>-7H-pyrrolo<2,3-d>pyrimidine 
• 104291-17-0 2-amino-4-chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 123439-73-6 2-amino-4-chloro-7-<2,3-dideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-β-D-glycero-pentofuranosyl>-7H-pyrrolo<2,3-d>pyrimidine 
• 111869-49-9 2-amino-7-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin-4(3H)-one 

Relevant academic research and scientific papers

Synthesis of 4-Substituted 2-Aminopyrrolopyrimidine 2',3'-Dideoxyribonucleosides

A number of new 2-aminopyrrolopyrimidine N-7-(2',3'-dideoxyribonucleosides) (11 - 13 and 15) were synthesized.These are related to 7-deaza-2',3'-dideoxyguanosine (14), but carry various substituents at C-4. 2-Amino-4-chloro-7-(2',3'-dideoxy-β-D-glycero-pentofuranosyl)-7H-pyrrolopyrimidine (3) was used as a common intermediate, and was obtained from the corrsponding 2'-deoxyribonucleoside 4 by selective silylation of 5'-OH and Barton deoxygenation of 3'-OH.