123534-49-6

Basic information

• Product Name: 2-(4-chlorophenyl)-4H-thiopyrano[2,3-b]pyridin-4-one
• CAS NO: 123534-49-6
• Molecular Weight: 273.743
• Mol File: 123534-49-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-4H-thiopyrano[2,3-b]pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-4H-thiopyrano[2,3-b]pyridin-4-one(123534-49-6)
• EPA Substance Registry System: 2-(4-chlorophenyl)-4H-thiopyrano[2,3-b]pyridin-4-one(123534-49-6)

Safety Data

• Hazardous Substances Data: 123534-49-6(Hazardous Substances Data)

Upstream product

• 827-72-5 4-chlorobenzimidic acid ethyl ester 
• 84199-61-1 1-(2′-bromo-3′-pyridyl)ethan-1-one 
• 13915-60-1 O-ethyl 4-chlorobenzenecarbothioate 
• 623-03-0 4-Cyanochlorobenzene 

Relevant articles and documents

Microwave-assisted three-component coupling-addition-SNAr (CASNAR) sequences to annelated 4H-thiopyran-4-ones

A whole family of annelated 4H-thiopyran-4-ones as the core structural unit was readily synthesized in good yields by a microwave-assisted coupling-addition-SNAr (CASNAR) sequence starting from readily available (het)aroyl chlorides, alkynes and sodium sulfide nonahydrate in a consecutive one-pot three-component reaction. All representatives display a pronounced halochromicity of the absorption bands upon protonation. According to DFT calculations, the electronic ground state of the annelated 4H-thiopyran-4-ones possess a considerable zwitterionic character. The Royal Society of Chemistry 2010.