123594-83-2Relevant academic research and scientific papers
4-Substituted anilides as selective melatonin MT2 receptor agonists
Epperson, James R.,Deskus, Jeffrey A.,Gentile, Anthony J.,Iben, Lawrence G.,Ryan, Elaine,Sarbin, Nathan S.
, p. 1023 - 1026 (2007/10/03)
A series of 4-substituted anilides with human melatonergic affinity is reported. Butyramides 26, 39, 42, 52, 57, and 58 all demonstrated subnanomolar MT2 binding affinity and MT2 selectivity of at least 70-fold over the MT1 receptor. Compound 26 demonstrated full agonism at the MT2 receptor.
Aryloxyanilides and related compounds
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, (2008/06/13)
There is provided novel aryloxyanilides and related compounds of the formula STR1 wherein R 1 is --OR, --CO 2 R, or halogen with R being C 1-4 alkyl;R 2 is R, cyclopropyl, C 2-4 alkenyl or --CH 2 OR; andX is O, S, CH 2, NR, SO, SO 2 or COwhich are melaton
Electrophilic aromatic substitution. 12. Kinectic studies of the TiCl4-catalyzed reactions of benzyl chloride, p-xylyl chloride, and p-nitrobenzyl chlordie with benzene and anisole in nitromehtane and dichloromethabe
DeHaan, Franklin P.,Chan, Wai H.,Chang, Jeffrey,Cheng, Terry B.,Chiriboga, Douglas A.,Irving, Mark M.,Kaufman, Craig R.,Kim, Gia Y.,Kumar, Amit,Na, Jim,Nguyen, Tien T.,Tim Nguyen,Patel, Bimal R.,Sarin, Neal P.,Tidwell, Jeffrey H.
, p. 356 - 363 (2007/10/02)
Through the use of vacuum line techniques, noncompetitive and competitive kinetic data have been obtained for the TiCl4-catalyzed reactions of benzyl chloride and p-methyl- and p-nitrobenzyl chloride with anisole and with benzene in solvents ni
