123618-06-4

Basic information

• Product Name: (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine
• Synonyms: (4S,5R)-3,4-Dimethyl-5-phenyl-1,3-oxazolidine; oxazolidine, 3,4-dimethyl-5-phenyl-, (4S,5R)-; Oxazolidine, 3,4-dimethyl-5-phenyl-, (4S-cis)-; Oxazolidine, 3,4-dimethyl-5-phenyl-, cis-
• CAS NO: 123618-06-4
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• Mol File: 123618-06-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 256.9°C at 760 mmHg
• Flash Point: 75.2°C
• Density: 1.012g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine(123618-06-4)
• EPA Substance Registry System: (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine(123618-06-4)

Safety Data

• Hazardous Substances Data: 123618-06-4(Hazardous Substances Data)

Usage

General Description

(4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine is a chemical compound that belongs to the oxazolidine family. It is a chiral molecule with two stereocenters, denoted as 4S and 5R. (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine is characterized by a five-membered ring containing an oxygen and a nitrogen atom. The presence of the phenyl group confers aromatic properties to the molecule. Oxazolidines have been widely studied for their potential applications in organic synthesis, catalysis, and pharmaceutical chemistry. The specific stereochemistry and substitution pattern of (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine may influence its reactivity and biological activity, making it a valuable target for further research and development.

Upstream product

• 50-00-0 formaldehyd 
• 1806-29-7 2,2'-dihydroxybiphenyl 
• 299-42-3 ephedrine 
• 75-09-2 dichloromethane 
• 90-81-3 ephedrine 
• 90-82-4 rac-pseudoephedrine 
• 1047392-28-8 methyl 2-(N-acetylamino)-5-ethynylbenzoate 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 462871-54-1 {[((1S,2R)-2-Chloro-1-methyl-2-phenyl-ethyl)-methyl-amino]-methyl}-phosphonic acid diethyl ester 
• 462871-70-1 ((2R,3S,4S)-1,4-Dimethyl-3-phenyl-azetidin-2-yl)-phosphonic acid diethyl ester 
• 462871-39-2 {[((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amino]-methyl}-phosphonic acid diethyl ester 
• 552-79-4 (-)-N-methylephedrine 
• 50-47-5 desipramine 
• 76503-86-1 (2R, 3S)-3,4,6-Trimethyl-7-morpholino-2-phenylhexahydro-1,4-oxazepin 
• 76503-94-1 (2R, 4S, 5R)-2-Isopropenyl-3,4-dimethyl-5-phenyl-1,3-oxazolidin 
• 76503-95-2 (2S, 4S, 5R)-2-Isopropenyl-3,4-dimethyl-5-phenyl-1,3-oxazolidin 
• 76503-87-2 (2R, 3S)-c-7-Dimethylamino-3,4,r-6-trimethyl-2-phenylhexahydro-1,4-oxazepin 
• 15451-14-6 3-dimethylamino-2,2-dimethylpropanal 
• 76503-82-7 3,4,6,6-Tetramethyl-7-dimethylamino-2-phenylhexahydro-1,4-oxazepin 
• 23588-51-4 2,2-dimethyl-3-(N-morpholino)propanal 
• 76503-78-1 3,4,6,6-Tetramethyl-7-morpholino-2-phenylhexahydro-1,4-oxazepin 
• 123387-83-7 (1R,2S)-2-[Methyl-(5-methyl-furan-2-ylmethyl)-amino]-1-phenyl-propan-1-ol 

Relevant articles and documents

Condensation of chiral 1,3-oxazolidines with cathecol and 4,4'- dibromobiphenol: New enantiopure polydentate ligands with C2-symmetry

The new enantiopure polydentate ligands 3a,c and 4a-c have been synthesized via Mannich condensation of 1,3-oxazolidines 1a-c with 5,5'- dibromobiphenol and cathecol. The products are enantiopure C2 chiral ligands of potential use in asymmetric synthesis as well as bioactive compounds.

Study of alkaloids of the Siberian and Altai flora 14. Synthesis of alkaloid-based tertiary N-(3-arylprop-2-ynyl)amines

3-Arylprop-2-ynylamines containing the key fragment of known alkaloids of the Altai flora were synthesized by the Sonogashira and Mannich reactions.

Reaction of 3-methylamino-1,2-diols with dihalomethanes. Synthesis of chiral 4-substituted 3-methyltetrahydro-1,3-oxazin-5-ols

Enantiomerically pure 4,5-disubstituted 3-methyltetrahydro-1,3-oxazines have been obtained by reaction of 3-methylamino-1,2-diols with dichloromethane by regioselective differentiation of hydroxyl groups. (C) 2000 Published by Elsevier Science Ltd.