1236429-55-2

Basic information

• Product Name: N-(4-(trifluoromethyl)thiazol-2-yl)benzamide
• Synonyms: N-(4-(trifluoromethyl)thiazol-2-yl)benzamide
• CAS NO: 1236429-55-2
• Molecular Weight: 272.251
• Mol File: 1236429-55-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-(trifluoromethyl)thiazol-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(trifluoromethyl)thiazol-2-yl)benzamide(1236429-55-2)
• EPA Substance Registry System: N-(4-(trifluoromethyl)thiazol-2-yl)benzamide(1236429-55-2)

Safety Data

• Hazardous Substances Data: 1236429-55-2(Hazardous Substances Data)

Upstream product

• 349-49-5 4-(trifluoromethyl)-1,3-thiazol-2-amine 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide

Head group analogues of the antibacterial and antiparasitic drug nitazoxanide (NTZ) are presented. A library of 39 analogues was synthesized and assayed for their ability to suppress growth of Helicobacter pylori, Campylobacter jejuni, Clostridium difficile and inhibit NTZ target pyruvate:ferredoxin oxidoreductase (PFOR). Two head groups assayed recapitulated NTZ activity and possessed improved activity over their 2-amino-5-nitrothiazole counterparts, demonstrating that head group modification is a viable route for the synthesis of NTZ-related antibacterial analogues.