1236889-51-2Relevant academic research and scientific papers
Pd(quinox)-catalyzed allylic relay Suzuki reactions of secondary homostyrenyl tosylates via alkene-assisted oxidative addition
Stokes, Benjamin J.,Bischoff, Amanda J.,Sigman, Matthew S.
, p. 2336 - 2339 (2014/05/20)
Pd-catalyzed allylic relay Suzuki cross-coupling reactions of secondary alkyl tosylates, featuring a sterically-hindered oxidative addition and precise control of β-hydride elimination, are reported. The identification of a linear free energy relationship between the relative rates of substrate consumption and the electronic nature of the substrate alkene suggests that the oxidative addition requires direct alkene involvement. A study of the effect of alkyl chain length on the reaction outcome supports a chelation-controlled oxidative addition. This journal is the Partner Organisations 2014.
Palladium-catalyzed hydroarylation of 1,3-dienes with boronic esters via reductive formation of π-Allyl palladium intermediates under oxidative conditions
Liao, Longyan,Sigman, Matthew S.
supporting information; experimental part, p. 10209 - 10211 (2010/09/05)
A palladium-catalyzed reductive cross-coupling of 1,3-dienes with boronic esters in which a π-allyl Pd species is generated directly from a 1,3-diene via a Pd-catalyzed aerobic alcohol oxidation is reported. Both the scope of the process and the origin of a highly selective 1,2-addition are discussed.
