1384458-53-0Relevant articles and documents
VINYLOGOUS PHENETHYLAMINES AS NEUROTRANSMITTER RELEASERS
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Paragraph 00121; 00123, (2017/12/02)
The disclosure provides monoamine neurotransmitter releaser and/or monoamine uptake inhibitor compounds having biogenic amine transporter activity but lacking substantial activity at 5-HT2 receptor subtypes. The phenethylamine or vinylogous phe
Pd(quinox)-catalyzed allylic relay Suzuki reactions of secondary homostyrenyl tosylates via alkene-assisted oxidative addition
Stokes, Benjamin J.,Bischoff, Amanda J.,Sigman, Matthew S.
, p. 2336 - 2339 (2014/05/20)
Pd-catalyzed allylic relay Suzuki cross-coupling reactions of secondary alkyl tosylates, featuring a sterically-hindered oxidative addition and precise control of β-hydride elimination, are reported. The identification of a linear free energy relationship between the relative rates of substrate consumption and the electronic nature of the substrate alkene suggests that the oxidative addition requires direct alkene involvement. A study of the effect of alkyl chain length on the reaction outcome supports a chelation-controlled oxidative addition. This journal is the Partner Organisations 2014.