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1237524-82-1

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1237524-82-1 Usage

General Description

2-Pyrazinecarboxamide, 3,4-dihydro-3-oxo-, sodium salt (1:1) is a chemical compound with the molecular formula C4H4N3O2Na. It is a sodium salt derived from 2-pyrazinecarboxamide, and it has the appearance of a white to off-white crystalline powder. This chemical is commonly used as a pharmaceutical intermediate in the production of various drugs. It may also have applications in other industries such as the manufacturing of dyes, pigments, and agricultural chemicals. The sodium salt form of this compound allows for easier handling and solubility in water, making it more suitable for various industrial and pharmaceutical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 1237524-82-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,7,5,2 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1237524-82:
(9*1)+(8*2)+(7*3)+(6*7)+(5*5)+(4*2)+(3*4)+(2*8)+(1*2)=151
151 % 10 = 1
So 1237524-82-1 is a valid CAS Registry Number.

1237524-82-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name sodium 2-carbamoylpyrazine-3-hydroxylate

1.2 Other means of identification

Product number -
Other names sodium 2-carbamoylpyrazine-3-hydroxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1237524-82-1 SDS

1237524-82-1Downstream Products

1237524-82-1Relevant articles and documents

A SIMPLE PROCESS FOR THE PREPARATION OF FAVIPIRAVIR AND ITS INTERMEDIATES THEREOF

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Page/Page column 8, (2022/01/04)

The present invention relates to a simple process for the preparation of Favipiravir of Formula (I). The present invention further relates to an improved process for the preparation of substantially pure 2-aminomalonamide of formula (II) a key starting material of Favipiravir.

Fapiravir and preparation method of intermediate thereof

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Paragraph 0048-0053; 0068-0070, (2020/12/08)

The invention relates to a fapiravir and a preparation method of an intermediate thereof, and belongs to the field of pharmaceutical chemicals. The invention provides a preparation method of a fapiravir intermediate 3-hydroxy sodium pyrazine-2-formamide, wherein the fapiravir intermediate 3-hydroxy sodium pyrazine-2-formamide is prepared by reacting aminopropanedioide with lithium chloride in thepresence of a NaOH solution and glyoxal. The invention also provides a preparation method of 6-bromo-3-hydroxy pyrazine-2-formamide, wherein the 6-bromo-3-hydroxy pyrazine-2-formamide is prepared froman acetonitrile solution of 3-hydroxy sodium pyrazine-2-formamide and an acetonitrile solution of liquid bromine in a microchannel reactor. The invention also provides a preparation method of 3, 6-difluoropyrazine-2-formamide, wherein the 3, 6-difluoropyrazine-2-formamide is prepared by reacting 6-bromo-3-hydroxy pyrazine-2-formamide with potassium bifluoride in the presence of PEG-400 and DMF. Finally, the invention also provides a total synthesis method for preparing fapiravir from the intermediate. The reactions avoid the use of highly dangerous diazotization reactions, and the methods have the advantages of high safety, low raw material price, short steps, low cost and simple post-treatment, and are suitable for industrial enlarged production.

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