123760-76-9Relevant academic research and scientific papers
Reduced Amino Acid Schiff Base-Iron(III) Complexes Catalyzing Oxidation of Cyclohexane with Hydrogen Peroxide
Zheng, Anna,Zhou, Qingqing,Ding, Bingjie,Li, Difan,Zhang, Tong,Hou, Zhenshan
, p. 3385 - 3395 (2021)
The reduced amino acid Schiff base ligands have been prepared and were coordinated with ferric chloride to generate the iron(III) complexes. The ligands and complexes have been characterized using FT-IR, UV-vis, elemental analysis, ICP-AES analysis, mass spectra etc. After the structural characterization, these complexes were applied for the oxidation of cyclohexane using hydrogen peroxide as the oxidant under mild conditions. The activity tests showed that the L-phenylalanine-derived reduced Schiff base iron(III) complex(Ph?FeCl) afforded the highest yield of cyclohexanol and cyclohexanone(total yield up to 23.2 %). Notably, the Ph?FeCl complex catalyzes the reaction via a heterogeneous approach, allowing the complex to be separated and recycled conveniently after the oxidation reaction. Besides, the Ph?FeCl catalyst can also be extended for the selective oxidation of other alkanes and aromatics into alcohols, ketones and phenols etc. Finally, the reaction mechanism of cyclohexane oxidation on the iron(III) complex was proposed as well by the free radical inhibitors and EPR study of active intermediates.
Designing isometrical gel precursors to identify the gelation pathway for nickel-selective metallohydrogels
Wang, Xiaojuan,He, Ting,Yang, Lan,Wu, Huiqiong,Yin, Jiafu,Shen, Rujuan,Xiang, Juan,Zhang, Yi,Wei, Chuanwan
, p. 18438 - 18442 (2016)
Two novel multi-responsive metallohydrogels, namely, 2-PF-Ni and 3-PF-Ni, were successfully constructed from phenylalanine derivatives. The 2-PF gelator shows specific responses to Ni2+; particularly, 2-PF-Ni is lavender colored, which has been rarely reported among hydrogels triggered by Ni2+. 3-PF-Ni is light green and exhibits perfect thixotropy. This paper provides insights into the gelation mechanisms of these two metallogels.
Amino acid derived CuII compounds as catalysts for asymmetric oxidative coupling of 2-naphthol
Ado, Pedro,Barroso, Snia,Carvalho, M. Fernanda N. N.,Teixeira, Carlos M.,Kuznetsov, Maxim L.,Costa Pessoa, Joo
supporting information, p. 1612 - 1626 (2015/02/19)
We report the synthesis and characterization of several novel aminopyridine-l-amino acid derived CuII-complexes. The ligands are prepared by a one-pot reductive alkylation of the l-amino acid scaffold and the respective aminopyridine CuII-complexes were obtained by reaction with CuCl2 or Cu(acetato)2. All compounds were characterized by spectroscopic techniques, as well as ESI-MS. Two of the CuII-complexes were characterized by single-crystal X-ray diffraction, one of them, [CuII(L)(CH3COO)] (HL = (S)-3-phenyl-2-(pyridin-2-ylmethylamino)propanoic acid), being the first ever reported aminopyridine-class CuII complex bearing a tridentate N,N,O donor set and a monodentate acetato ligand. The complexes are tested as catalysts in the oxidative coupling of 2-naphthol in organic solvent-water mixtures using dioxygen as the terminal oxidant. The effect of variables such as ligand denticity and substituents, as well as solvent, temperature and oxidant intake, on the overall performance is studied. In general, moderate to low conversions of 2-naphthol to 1,1′-bi-2-naphthol (BINOL) are obtained. The catalysts also showed moderate to low enantioselectivity. Some aspects of the reaction mechanism were elucidated by spectroscopy, electrochemical and theoretical studies. It was found that basic additives are important for activity, but these also increase the formation of secondary oxidation products. The addition of peroxide scavengers such as KI resulted in an increase of conversion, the yield of BINOL and enantioselectivity. This journal is
N-SUBSTITUTED AMINO ACID DERIVATIVES WITH HYPERALPHALIPOPROTEINAEMIC ACTIVITY
Baggaley, Keith H.,Fears, Robin,Ferres, Harry,Geen, Graham R.,Hatton, Ian K.,et al.
, p. 523 - 532 (2007/10/02)
A series of N-substituted amino acid derivatives was synthesized and the compounds were evaluated for their effects on serum total cholesterol, HDL cholesterol and triglycerides in experimental animals.Hyperalphalipoproteinaemic activity was found for some of these compounds tested, especially BRL 26314 (2) and related 3-aryl-2-aminopropionic acids.Structure-activity relationships are discussed.Keywords: N-substituted amino acid derivatives / hyperalphalipoproteinaemic activity
