123802-17-5Relevant articles and documents
New Synthetic Methodology for the Synthesis of 7-Substituted Tetrahydroazepin-2-ones
Evans, P. Andrew,Holmes, Andrew B.,Russell, Keith
, p. 3397 - 3410 (2007/10/02)
The Claisen rearrangement of the vinyl substituted ketene aminals 2 (R = CH2CHMe2, CH2OSit-BuMe2) which were generated in situ by selenoxide elimination of the aminal precursors 3 in the presence of 1,8-diazabicycloundec-7-ene (DBU) furnished the enantiomerically pure 7-substituted tetrahydroazepin-2-ones 1.
N-ACYLAMINO ACID DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS
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, (2008/06/13)
An N-acylamino acid derivative of the formula: STR1 wherein the substituents are herein defined or a salt thereof, which is useful as hypotensive drugs.
Synthesis Of Homochiral Unsaturated Seven-Membered Lactams
Evans, P. Andrew,Holmes, Andrew B.,Russell, Keith
, p. 593 - 596 (2007/10/02)
The Claisen rearrangement of the vinyl substituted ketene aminals 6 which were generated in situ by selenoxide elimination of the aminal precursors 5 in the presence of 1,8-diazabicycloundec-7-ene (DBU) gave the homochiral unsaturated seven-membere