166735-51-9

Usage

Uses

Used in Pharmaceutical Industry:
N-Z-D-LEUCINOL 97 is used as a chiral building block for the synthesis of enantiopure drugs, ensuring the production of pharmaceuticals with the desired biological activity and minimizing potential side effects associated with impurities or unwanted enantiomers.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, N-Z-D-LEUCINOL 97 serves as a key component in the development of enantiomerically pure agrochemicals, contributing to the effectiveness and selectivity of these compounds in agricultural applications.
Used in Organic Synthesis:
N-Z-D-LEUCINOL 97 is utilized as a solvent or intermediate in organic synthesis, facilitating various chemical reactions and contributing to the creation of complex organic molecules for a multitude of purposes.
Used in Production of Enantiopure Compounds:
N-Z-D-LEUCINOL 97 is employed in the production of enantiopure compounds, which are essential in various scientific and industrial processes where the stereochemistry of molecules plays a critical role in their function and interaction.

InChI:InChI=1/C14H21NO3/c1-11(2)8-13(9-16)15-14(17)18-10-12-6-4-3-5-7-12/h3-7,11,13,16H,8-10H2,1-2H3,(H,15,17)/t13-/m1/s1

Upstream product

• 1070268-73-3 benzyl 1-isobutyl-2,2-dimethoxyethylcarbamate 
• 1084820-40-5 1,1-dimethoxy-4-methylpentan-2-one oxime 
• 1217341-11-1 C₁₅H₂₅NO₂ 
• 70853-26-8 O-benzyl-N-(4-methyl-1-oxopentan-2-yl)carbamid acid 
• 328-39-2 LEUCINE 

Downstream Products

• 1235475-90-7 2-(benzyloxycarbonylamino)-4-methylpentyl acetate 
• 1235475-86-1 C₁₆H₂₃NO₄ 
• 1374636-02-8 [2-(benzyloxycarbonylamino)-4-methyl-pentyl] methanesulfonate 
• 1374635-40-1 benzyl N-[1-(aminomethyl)-3-methyl-butyl]carbamate 
• 1391936-85-8 benzyl N-[1-(azidomethyl)-3-methyl-butyl]carbamate 
• 1374635-41-2 tert-butyl N-[2-(benzyloxycarbonylamino)-4-methyl-pentyl]carbamate 
• 177777-70-7 (+/-)-3-[(Benzyloxycarbonyl)amino]-5-methylhexan-2-one 
• 70853-26-8 O-benzyl-N-(4-methyl-1-oxopentan-2-yl)carbamid acid 
• 132065-40-8 3-benzyloxycarbonyl-4-isobutyl-2-phenylselenanylmethyl-5-vinyloxazolidine 
• 145632-69-5 (+/-)-1-benzyloxycarbonyl-7-isobutyl-1,3,4,7-tetrahydroazepin-2-one 
• 123802-17-5 4-benzyloxycarbonylamino-6-methylhept-1-en-3-ol 

Relevant academic research and scientific papers

Synthesis and evaluation of chirally defined side chain variants of 7-chloro-4-aminoquinoline to overcome drug resistance in malaria chemotherapy

A novel 4-aminoquinoline derivative [(S)-7-chloro-N-(4-methyl-1-(4-methyl-piperazin-1-yl)pentan-2-yl)-quinolin-4-amine triphosphate] exhibiting curative activity against chloroquine-resistant malaria parasites has been identified for preclinical development as a blood schizonticidal agent. The lead molecule selected after detailed structure-activity relationship (SAR) studies has good solid-state properties and promising activity against in vitro and in vivo experimental malaria models. The in vitro absorption, distribution, metabolism, and excretion (ADME) parameters indicate a favorable drug-like profile.

Resolution and absolute configuration of some a-aminoacetals: En route to enantiopure N-protected a-aminoaldehydes

The first successful resolution of rac-a-aminoacetals via diastereoisomeric salt formation with optically pure N-protected aminoacids is reported. The absolute configuration assignment of a-aminoacetal enantiomers is performed by an entirely non-racemizing chemical correlation method involving N-protection and a new efficient hydrolysis step followed by a reduction of the resulting N-protected a-aminoaldehyde intermediates. A racemization method of optically enriched a-aminoacetals is exemplified to allow valorisation of both enantiomers. Springer-Verlag 2011.

A mild chemoselective and rapid regeneration of alcohols from O-allyl ethers by LiCl/NaBH4

An efficient chemoselective cleavage of O-allyl protected is developed employing LiCl/NaBH4.

A Mild and Rapid Regeneration of Alcohols from Allyl Ethers by ZrCl4/NaBH4

A new extremely facile, spontaneous and efficient cleavage of allyl protection is developed employing ZrCl4/NaBH4.

1-N-substituted derivatives of 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols

Novel 1-N-aminoalkyl (oxycarbonyl or carboxamido or thiocarboxamido) derivatives of 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, useful as antibacterial agents, are described.