123811-75-6 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
4-(tert-Butyl)picolinic acid hydrochloride is utilized as a research compound for its potential to target choline binding sites in the brain, which is instrumental in the development of drugs that can modulate these sites for therapeutic purposes.
Used in Neurological Applications:
In the field of neurology, 4-(tert-Butyl)picolinic acid hydrochloride is employed as a potential neuroprotective agent, leveraging its capacity to shield the brain from damage and degeneration, thereby contributing to the treatment and management of neurodegenerative diseases.
Used in Antioxidant Therapies:
4-(tert-Butyl)picolinic acid hydrochloride is used as an antioxidant, given its potential to combat oxidative stress, a common factor in various pathological conditions, thus offering a means to mitigate cellular damage and promote overall health.
Used in Medicinal Chemistry:
Within the domain of medicinal chemistry, 4-(tert-Butyl)picolinic acid hydrochloride serves as a key compound in the discovery and synthesis of new drugs, particularly those aimed at modulating cholinergic neurotransmission and offering neuroprotective benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 123811-75-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,1 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 123811-75:
(8*1)+(7*2)+(6*3)+(5*8)+(4*1)+(3*1)+(2*7)+(1*5)=106
106 % 10 = 6
So 123811-75-6 is a valid CAS Registry Number.
123811-75-6Relevant academic research and scientific papers
An Improved Synthesis of Homoproline and Derivatives
Shuman, Robert T.,Ornstein, Paul L.,Paschal, Jonathan W.,Gesellchen, Paul D.
, p. 738 - 741 (2007/10/02)
An improved, general synthesis of substituted homoprolines has been developed by using readily available substituted pyridines (1).A key step in this synthetic procedure involves the known conversion of pyridine-N-oxides to 2-cyanopyridines (3) in nearly quantitative yields.The resulting nitriles are hydrolyzed to the corresponding pyridine-2-carboxylic acids (4).Subsequent reduction of the aromatic ring with PtO2/H2 gives the homoprolines (5) in good yields as racemic cis isomers.This procedure also can be utilized for the preparation of 5,6-benzohomoprolines fromthe appropriate quinoline precursors.The N-tert-butyloxycarbonyl (Boc) derivatives of these amino acids (useful intermediates for peptide synthesis) were also prepared in good yields.
