23569-17-7

Usage

Uses

Used in Organic Synthesis:
4-TERT-BUTYLPYRIDINE 1-OXIDE is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the formation of complex organic molecules.
Used in Polymer Stabilization:
In the polymer industry, 4-TERT-BUTYLPYRIDINE 1-OXIDE is used as a stabilizer to enhance the durability of materials. It helps in preventing the degradation of polymers, thereby extending their service life.
Used in Rubber and Plastic Production:
4-TERT-BUTYLPYRIDINE 1-OXIDE is utilized in the production of rubber and plastic products to improve their resistance to oxidation and degradation. Its antioxidant properties play a crucial role in maintaining the integrity and performance of these materials over time.
Used in Pharmaceuticals:
Due to its unique chemical properties, 4-TERT-BUTYLPYRIDINE 1-OXIDE has potential applications in the pharmaceutical industry. It may be employed in the development of new drugs or as an intermediate in the synthesis of pharmaceutical compounds.
Used in Agrochemicals:
Similarly, in the agrochemical sector, 4-TERT-BUTYLPYRIDINE 1-OXIDE may find use due to its distinctive characteristics, potentially contributing to the development of new agrochemical products or as a component in existing ones.

InChI:InChI=1/C9H13NO/c1-9(2,3)8-4-6-10(11)7-5-8/h4-7H,1-3H3

Upstream product

• 3978-81-2 4-tert-butylpyridine 

Downstream Products

• 42205-73-2 4-tert-butyl-2-cyanopyridine 
• 55930-28-4 1-Benzyloxy-4-tert-butyl-pyridinium; bromide 
• 3978-81-2 4-tert-butylpyridine 
• 42205-74-3 4-tert-Butylpyridine-2-carboxylic acid 
• 261777-43-9 (2S,4S)-trans-4-(tert-butyl)-1,2-piperidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester 
• 261777-40-6 (2R,4S)-cis-4-(tert-butyl)-1,2-piperidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester 
• 261777-35-9 (2R,4S)-cis-4-(tert-butyl)-1,2-piperidinedicarboxylic acid 1-(phenylmethyl) ester 
• 166897-61-6 N,N'-(4,5-dichloro-o-phenylene)bis(4-tert-butylpyridine-2-carboxamide) 
• 123811-75-6 4-tert-Butyl-pyridine-2-carboxylic acid; hydrochloride 
• 80005-85-2 [Rh(COD)(4-t-BuPyO)(PPh₃)]ClO₄ 
• 33091-19-9 C₁₇H₁₆F₄N₂ 
• 33091-18-8 2,3,3,3-tetrafluoropropionic toluamide 
• 1032509-17-3 p-methoxybenzyl 2-(4'-tert-butylpyridin-2'-yl)perfluoropropionate 
• 1277098-69-7 C₂₄H₂₄N₂O 

Relevant academic research and scientific papers

Synthesis and structural characterization of tris(2-pyridonyl)methyl complexes of zinc and thallium: A new class of metallacarbatranes and a monovalent thallium alkyl compound

Tris(2-pyridonyl)methanes may be synthesized via the reactions of the respective 2-pyridone with CHX3 (X = Cl, Br) and K2CO 3 in the presence of [Bun4N]Br, followed by acid-catalyzed isomerization wit

Urea-functionalized M4L6 cage receptors: Anion-templated self-assembly and selective guest exchange in aqueous solutions

We present an extensive study of a novel class of de novo designed tetrahedral M4L6 (M = Ni, Zn) cage receptors, wherein internal decoration of the cage cavities with urea anion-binding groups, via functionalization of the organic components L, led to selective encapsulation of tetrahedral oxoanions EO4n- (E = S, Se, Cr, Mo, W, n = 2; E = P, n = 3) from aqueous solutions, based on shape, size, and charge recognition. External functionalization with tBu groups led to enhanced solubility of the cages in aqueous methanol solutions, thereby allowing for their thorough characterization by multinuclear (1H, 13C, 77Se) and diffusion NMR spectroscopies. Additional experimental characterization by electrospray ionization mass spectrometry, UV-vis spectroscopy, and single-crystal X-ray diffraction, as well as theoretical calculations, led to a detailed understanding of the cage structures, self-assembly, and anion encapsulation. We found that the cage self-assembly is templated by EO4n- oxoanions (n ≥ 2), and upon removal of the templating anion the tetrahedral M4L6 cages rearrange into different coordination assemblies. The exchange selectivity among EO4n- oxoanions has been investigated with 77Se NMR spectroscopy using 77SeO42- as an anionic probe, which found the following selectivity trend: PO 43- ? CrO42- > SO 42- > SeO42- > MoO 42- > WO42-. In addition to the complementarity and flexibility of the cage receptor, a combination of factors have been found to contribute to the observed anion selectivity, including the anions' charge, size, hydration, basicity, and hydrogen-bond acceptor abilities.

Substituted 2,2′-bipyridines by nickel catalysis: 4,4′-Di- tert -butyl-2,2′-bipyridine

A simple, ligand-free synthesis of the important bipyridyl ligand 4,4′-di-tert-butyl-2,2′-bipyridine is presented. 5,5′-Bis(trifluoromethyl)-2,2′-bipyridine is also synthesized by the same protocol. The syntheses efficiently couple the parent 2-chloropyridines by a nickel-catalyzed dimerization with manganese powder as the terminal reductant. Georg Thieme Verlag Stuttgart New York.

Ozone-Mediated Amine Oxidation and Beyond: A Solvent-Free, Flow-Chemistry Approach

Ozone is a powerful oxidant, most commonly used for oxidation of alkenes to carbonyls. The synthetic utility of other ozone-mediated reactions is hindered by its high reactivity and propensity to overoxidize organic molecules, including most solvents. This challenge can largely be mitigated by adsorbing both substrate and ozone onto silica gel, providing a solvent-free oxidation method. In this manuscript, a flow-based packed bed reactor approach is described that provides exceptional control of reaction temperature and time to achieve improved control and chemoselectivity over this challenging transformation. A powerful method to oxidize primary amines into nitroalkanes is achieved. Examples of pyridine, C-H bond, and arene oxidations are also demonstrated, confirming the system is generalizable to diverse ozone-mediated processes.

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.

Organometallic complex and Organic light emitting diode comprising the same

An organometallic complex and an organic light emitting device including the same are disclosed. (by machine translation)

Electrochemical Deoxygenation of N-Heteroaromatic N -Oxides

An electrochemical method for the deoxygenation of N-heteroaromatic N -oxide to give the corresponding N-heteroaromatics has been developed. Several classes of N-heterocycles such as pyridine, quinoline, isoquinoline, and phenanthridine are tolerated. The electrochemical reactions proceed efficiently in aqueous solution without the need for transition-metal catalysts and waste-generating reducing reagents.

Visible Light-Mediated Decarboxylative Alkylation of Pharmaceutically Relevant Heterocycles

A net redox-neutral method for the decarboxylative alkylation of heteroarenes using photoredox catalysis is reported. Additionally, this method features the use of simple, commercially available carboxylic acid derivatives as alkylating agents, enabling the facile alkylation of a variety of biologically relevant heterocyclic scaffolds under mild conditions.

Nickel-catalyzed C–H trifluoromethylation of pyridine N-oxides with Togni's reagent

The first nickel-catalyzed C–H trifluoromethylation of pyridine N-oxides with Togni's reagent has been achieved. Trifluoromethylation proceeds smoothly under mild conditions with moderate functional group compatibility. Notable advantages of this method include the using of low cost of nickel catalyst, and its simple convenient operation.

ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME

PROBLEM TO BE SOLVED: To provide a compound which has an electron-donating property and is stable in the atmosphere. SOLUTION: The organic compound is represented by general formula [1] (where n represents an integer from 0 to 3 inclusive; R1 and R4 each represent an alkyl group or an aryl group selected from a phenyl group, a naphthyl group, a biphenyl group, a terphenyl group, a phenanthrenyl group, a fluorenyl group, and a fluoranthenyl group; when R1 or R4 is an aryl group, the aryl group may further have an alkyl group; R2 and R3 each represent an alkyl group or an aryl group selected from a phenyl group, a naphthyl group, a biphenyl group, a terphenyl group, a phenanthryl group, a fluorenyl group, and a fluoranthenyl group; when R2 or R3 is an aryl group, the aryl group may further have an alkyl group, a phenyl group, or a naphthyl group; when R1 and R4 are alkyl groups, R2 and R3 are aryl groups; and when R2 and R3 are alkyl groups, R1 and R4 are aryl groups). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT