123836-10-2

Upstream product

• 1474-14-2 3β-acetoxybisnor-5-cholenic acid 
• 67711-02-8 3β-acetoxy-23,24-dinorchol-5-en-22-oyl chloride 
• 33168-65-9 methyl 3β-acetoxy-24-norchol-5-en-23-oate 
• 123836-08-8 5α,8α-(3,5-dioxo-4-phenyl-1,2,4-triazolino)-24,24-difluoro-26,27-dimethylcholest-6-ene-3β,25-diol 3-acetate 
• 123836-01-1 ethyl 24,24-difluoro-23-<oxy>-3β-(methoxymethoxy)homochol-5-en-25-oate 
• 174293-44-8 ethyl 24,24-difluoro-23-hydroxy-3β-(methoxymethoxy)homochol-5-en-25-oate 
• 106647-58-9 24,24-difluoro-26,27-dimethylcholest-5-ene-3β,25-diol 3-acetate 
• 106647-59-0 24,24-difluoro-26,27-dimethylcholesta-5,7-diene-3,25-diol 
• 123836-09-9 (R)-3-{(Z)-2-[(1R,3aR,7aR)-1-((R)-5-Ethyl-4,4-difluoro-5-hydroxy-1-methyl-heptyl)-7a-methyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]-vinyl}-4-methyl-cyclohex-3-enol 
• 123836-06-6 24,24-difluoro-26,27-dimethylcholest-5-ene-3β,25-diol 
• 123835-97-2 methyl 3β-(methoxymethoxy)-24-norchol-5-en-23-oate 
• 111478-66-1 3β-(methoxymethoxy)-24-norchol-5-en-23-al 
• 69454-96-2 methyl 3β-hydroxy-24-nor-5-cholen-23-oate 
• 106647-61-4 24,24-Difluoro-25-hydroxy-26,27-dimethylvitamin D₃ 

Downstream Products

• 123836-14-6 Acetic acid (1R,5S)-3-[2-[(1R,3aS,7aR)-1-((R)-5-ethyl-4,4-difluoro-5-hydroxy-1-methyl-heptyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-5-hydroxy-4-methylene-cyclohexyl ester 
• 123836-13-5 24,24-difluoro-1α,25-dihydroxy-26,27-dimethylvitamin D3 3-acetate 

Relevant academic research and scientific papers

Synthesis and Biological Activity of Novel Vitamin D Analogues: 24,24-Difluoro-25-hydroxy-26,27-dimethylvitamin D3 and 24,24-Difluoro-1α,25-dihydroxy-26,27-dimethylvitamin D3

We synthesized 24,24-difluoro-25-hydroxy-26,27-dimethylvitamin D3 (16) and 24,24-difluoro-1α,25-dihydroxy-26,27-dimethylvitamin D3 (21), from 3β-hydroxy-22,23-dinorcholenic acid 3-acetate.Compound 16 was found to be a highly potent v