41865-47-8

Upstream product

• 2761-33-3 2-acetoxytetrahydropyran 
• 7677-24-9 trimethylsilyl cyanide 
• 100-52-7 benzaldehyde 
• 4657-12-9 sodium hydroxy(phenyl)methanesulfonate 

Downstream Products

• 95514-58-2 2-Phenyl-2-(tetrahydro-pyran-2-yloxy)-pent-4-enenitrile 
• 2248-17-1 γ-fluorobutyrophenone 
• 119657-20-4 (4-nitrophenyl)phenyl(tetrahydropyranoxy)acetonitrile 
• 70098-89-4 5-phenoxy-1-phenylpentan-1-one 
• 495-41-0 1-phenylbut-2-en-1-one 
• 43058-55-5 Allylphenylketoncyanhydrin 
• 119657-21-5 <4-nitro-3-(phenylsulfonylmethyl)phenyl>phenyl(tetrahydropyranoxy)acetonitrile 
• 119657-03-3 4-nitro-3-(phenylsulfonylmethyl)benzophenone 
• 123837-01-4 (1Z)-N'-hydroxy-2-phenyl-2-(tetrahydro-2H-pyran-2-yloxy)ethanimidamide 
• 173484-24-7 5-(p-valerylphenoxy)-1-phenylpentan-1-one 
• 173484-22-5 4-(p-valerylphenoxy)-1-phenylbutan-1-one 
• 173484-23-6 5-(p-acetylphenoxy)-1-phenylpentan-1-one 
• 173484-21-4 4-(p-acetylphenoxy)-1-phenylbutan-1-one 
• 681124-12-9 acetic acid 10-{tert-butoxycarbonyl-[3-(tert-butoxycarbonyl-{4-[tert-butoxycarbonyl-(3-tert-butoxycarbonylamino-propyl)-amino]-butyl}-amino)-propyl]-amino}-1-cyano-1-phenyl-dec-5-ene-3,7-diynyl ester 

Relevant academic research and scientific papers

Iron(III) triflate-catalyzed one-pot synthesis of acetal-type protected cyanohydrins from carbonyl compounds

A variety of cyanohydrin THP ethers were readily prepared from carbonyl compounds with trimethylsilyl cyanide and tetrahydropyran-2-yl acetate under the influence of a catalytic amount of iron(III) triflate in a convenient one-pot procedure. This method was also effective to prepare O-protected cyanohydrins by various acetal-type protective groups.

Metabolites of the Higher Fungi. Part 19. Serpenone, 3-Methoxy-4-methyl-5-prop-1-enylfuran-2(5H)-one, a new γ-Butyrolactone from the Fungus Hypoxylon serpens (Barrons strain) (Persoon ex Fries)Kickx

Culture solutions of the fungus Hypoxylon serpens (Barrons strain) contain a new butyrolactone as the major metabolite, which has been identified as 3-methoxy-4-methyl-5-prop-1-enylfuran-2(5H)-one (2),and small quantities of the reduced analogue, 3-methoxy-4-methyl-5-propylfuran-2(5H)-one (3); the structures have been established by synthesis of compound (3).A new rapid synthesis of the isomeric 4-methoxy-3,5-disubstituted analogues is described and the two groups of compounds are compared spectroscopically.