123843-65-2

Usage

Uses

Used in Organic Synthesis:
2,6-Difluoro-4-methoxybenzoic acid is used as a building block in organic synthesis for the creation of various biologically active compounds. Its unique structure allows for the development of new molecules with potential applications in different fields.
Used in Pharmaceutical Research:
In pharmaceutical research, 2,6-difluoro-4-methoxybenzoic acid serves as a key intermediate for the synthesis of drugs with therapeutic potential. Its incorporation into drug molecules can enhance their efficacy and selectivity, contributing to the advancement of novel treatments.
Used in Fragrance and Flavoring Industry:
2,6-Difluoro-4-methoxybenzoic acid is utilized in the production of fragrances and flavoring agents. Its unique chemical structure imparts distinct scents and tastes, making it a valuable component in the creation of various consumer products.
Used in Anti-Inflammatory and Analgesic Applications:
2,6-Difluoro-4-methoxybenzoic acid has been studied for its potential pharmacological properties, including anti-inflammatory and analgesic effects. Its ability to modulate inflammatory pathways and alleviate pain makes it a promising candidate for the development of new medications to treat inflammatory disorders and pain conditions.

InChI:InChI=1/C8H6F2O3/c1-13-4-2-5(9)7(8(11)12)6(10)3-4/h2-3H,1H3,(H,11,12)

Upstream product

• 93343-10-3 3,5-difluoroanisol 
• 124-38-9 carbon dioxide 
• 2713-34-0 3,5-difluorophenol 
• 123843-66-3 2,6-Difluoro-4-methoxybenzonitrile 

Downstream Products

• 125369-56-4 2,6-difluoro-4-methoxybenzoyl chloride 
• 125369-57-5 2,6-difluoro-4-methoxybenzamide 
• 601517-02-6 2-amino-6-fluoro-4-methoxybenzonitrile 
• 601516-55-6 2-fluoro-6-iodo-4-methoxy-benzonitrile 
• 601516-61-4 2-amino-6-iodo-4-methoxy-benzonitrile 
• 880885-37-0 2-amino-4-methoxy-6-pyrazol-1-yl-benzonitrile 
• 880885-42-7 2-amino-4-methoxy-6-thiazol-2-yl-benzonitrile 
• 880885-39-2 2-amino-4-methoxy-6-(3-methyl-pyrazol-1-yl)-benzonitrile 
• 880885-40-5 2-amino-4-methoxy-6-(2-methyl-2H-pyrazol-3-yl)-benzonitrile 
• 880885-38-1 2-amino-6-(4-chloro-pyrazol-1-yl)-4-methoxy-benzonitrile 
• 880885-41-6 2-amino-6-(2-ethoxymethyl-2H-pyrazol-3-yl)-4-methoxy-benzonitrile 
• 123843-66-3 2,6-Difluoro-4-methoxybenzonitrile 
• 84937-82-6 methyl 2,6-difluoro-4-methoxybenzoate 
• 1188927-57-2 C₁₄H₁₈F₂O₃ 

Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS

The present application relates to novel quinazoline compounds as inhibitors of type I receptor tyrosine kinases, the pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and the use of the compounds and salts thereof in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals and especially in humans.

AROMATIC COMPOUND

Provided is a novel aromatic ring compound having a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity and a GLP-1 secretagogue action, is useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and affords superior efficacy.

Synthesis of 5-heterocyclic substituted quinazolin-4-ones via 2-aminobenzonitrile derivatives

Two routes to prepare a series of six 5-heterocyclic substituted 2-chloro-7-methoxyquinazolin-4-ones are described, where the heterocycle is a substituted or unsubstituted 1-pyrazolyl, 5-pyrazolyl or 2-thiazolyl group. Both routes proceeded via key 2-amin

A convenient synthesis of 4-alkoxy- and 4-hydroxy-2,6-difluoroanilines

Two independent synthetic pathways for the preparation of 4-methoxy, 4-benzyloxy and 4-hydroxy-2,6-difluoroanilines, versatile building blocks in medicinal chemistry, based on diazonium coupling or Curtius-type rearrangements are presented.

Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same

A compound represented by the following general formula (I), a liquid crystal composition comprising the same, and a liquid crystal element using this liquid crystal composition. (wherein B1 and B2 represent independently a trans-1,4-cyclohexylene group o

Laterally fluorinated 4-cyanophenyl and 4'-cyanobiphenyl benzoates

Laterally fluorinated 4-cyanophenyl and 4'-cyanobiphenyl benzoates are diosed of general formula I: STR1 in which R is R1 or R1 O, wherein R1 is C1 -C12 alkyl, m and n are 0 or 1 provided that (n+m) is 0 or 1, each of a, b, c and d are independently 0 or 1, provided (a+b+c+d) is not zero, but excluding the case where a and b are 0 and one of c and d is 0, being useful constituents of nematic liquid crystal materials.

The Synthesis and Transition Temperatures of Some Fluoro-Substituted 4-Cyanophenyl and 4-Cyanobiphenyl-4'-yl 4-Pentyl- and 4-Butoxy-Benzoates

A series of 4-cyanophenyl 4-X-benzoates and a series of 4-cyanobiphenyl-4'-yl 4-X-benzoates (X= pentyl, butoxy) have been prepared without fluoro-substitution and with mono-fluoro to tetra-fluoro-substitution; all possible combinations of substitution patterns at the positions ortho- to the cyano group and ortho- to the carboxylate group have been obtained in an attempt to determine the structural features which are responsible for some members of these series showing very large positive values of dielectric anisotropy.The synthesis of novel precursors required for the preparation of these esters is described and the melting points and transition temperatures of the esters are discussed and an explanation is provided for the variation of Tn-1 values with position and extent of fluoro-substitution. - Keywords: Fluoro-substitution, phenyl and biphenyl benzoates, terminal cyano namatogens.