123862-94-2Relevant academic research and scientific papers
Hypervalent Iodine(III)-Promoted Phenyl Transfer Reaction from Phenyl Hydrazides to Nitriles
Yan, Yan,Zhang, Zhiguo,Wan, Yameng,Zhang, Guisheng,Ma, Nana,Liu, Qingfeng
, p. 7957 - 7963 (2017)
A useful transformation of nitriles to N-phenyl amides has been achieved through a novel intermolecular phenyl transfer reaction from phenyl hydrazides and N-addition to nitriles in the presence of PIFA under mild and solvent-free conditions. This cross-coupling reaction includes the oxidative cleavage of sp2 C-N bonds of phenyl hydrazides to form a phenyl radical and the subsequent N-addition to cyanos to form new sp2 C-N bonds and provides efficient access to various N-phenyl amides in moderate to good yields under mild reaction conditions.
AMIDE COUPLING PROCESS
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Page/Page column 13; 17, (2022/03/07)
The present invention relates to a synthetic process for amide coupling between a trihaloketone and an electron poor nucleophile, amenable to large scale synthesis, in particular, through a catalytic process.
An Atom-Economical Method for the Formation of Amidopyrroles Exploiting the Self-Assembled Resorcinarene Capsule
De Rosa, Margherita,Gaeta, Carmine,La Manna, Pellegrino,Neri, Placido,Soriente, Annunziata,Talotta, Carmen
supporting information, (2020/04/02)
Here is reported the first example of an organocatalyzed coupling between pyrrole and isocyanates in a nanoconfined space. The hexameric resorcinarene capsule C is able to catalyze the direct coupling between isocyanates and pyrroles to give amidopyrroles
Conformational Properties of Aromatic Oligoamides Bearing Pyrrole Rings
Tojo, Yukiko,Urushibara, Ko,Yamamoto, Sawori,Mori, Hirotoshi,Masu, Hyuma,Kudo, Mayumi,Hirano, Tomoya,Azumaya, Isao,Kagechika, Hiroyuki,Tanatani, Aya
, p. 4606 - 4617 (2018/04/26)
N-Alkylbenzanilides generally exist in cis conformation both in the crystalline state and in various solvents, and this cis conformational preference can be utilized to construct dynamic helical oligoamides. Here, we synthesized the pyrrole-containing ami
Facile and Effective Synthesis of Unusually Substituted Aromatic N-Phenylamides
Kobs, Uwe,Neumann, Wilhelm P.
, p. 2191 - 2194 (2007/10/02)
A mild and effective new method for the preparation of a variety of arylamides 3a-i as well as heterocyclic 5a, b and 6 and olefinic amides 7, 9 is described.The reaction of trialkylstannyl-substituted aromatic, heterocyclic or vinylic hydrocarbons with aryl isocyanates in the presence of aluminium trichloride provides the corresponding N-aryl-substituted amides in good to excellent yields.The stannyl group serves as a powerful leaving group superior to hydrogen by several powers of ten which allows, via ipso substitution, to obtain isomer patterns not accessible by normal electrophilic substitution reactions, e. g. substitution in meta position with respect to a methoxy group.
