123979-03-3Relevant articles and documents
An in vivo active 1,2,5-oxadiazole Pt(II) complex: A promising anticancer agent endowed with STAT3 inhibitory properties
Porta, Federica,Facchetti, Giorgio,Ferri, Nicola,Gelain, Arianna,Meneghetti, Fiorella,Villa, Stefania,Barlocco, Daniela,Masciocchi, Daniela,Asai, Akira,Miyoshi, Nao,Marchianò, Silvia,Kwon, Byoung-Mog,Jin, Yena,Gandin, Valentina,Marzano, Cristina,Rimoldi, Isabella
, p. 196 - 206 (2017)
New Pt(II) complexes (Pt-1-3) bearing 1,2,5-oxadiazole ligands (1-3) were synthesized, characterized and evaluated for their ability to disrupt STAT3 dimerization. Ligand 3·HCl showed cytotoxic effects on HCT-116 cells (IC50 = 95.2 μM) and a se
Reaction of Z isomers of alkylaromatic 1,2-hydroxylamino oximes with 1,2-diketones
Amitina,Grigor'ev,Tikhonov
, p. 1046 - 1051 (2008/02/01)
The reactions of Z isomers of alkylaromatic 1,2-hydroxylamino oximes containing the hydroxylamino group at the primary or secondary carbon atom with diacetyl afford 6-acetyl-5,6-dihydro-4H-1,2,5-oxadiazines. The reactions of these compounds with alkylaromatic 1,2-diketones produce N-substituted α-aroylnitrones or 6-aroyl-5,6-dihydro-4H-1,2,5-oxadiazines or, alternatively, their tautomeric mixtures.