123989-25-3

Upstream product

• 67-56-1 methanol 
• 62515-35-9 (1SR,5RS,6RS,7RS)-6-<4-(3-chlorophenoxy)-3-oxobut-1(E)-en-1-yl>-7-trimethylsiloxy-2-oxabicyclo<3.3.0>octan-3-one 

Downstream Products

• 53872-62-1 (3aS,4S,6aR)-4-[(E)-4-(3-Chloro-phenoxy)-3-oxo-but-1-enyl]-5-hydroxy-hexahydro-cyclopenta[b]furan-2-one 
• 130214-53-8 (1SR,2RS,6SR,8RS,12RS)10-(3-chlorophenoxymethyl)-10-hydroxy-12-methoxy-5.9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 
• 129988-14-3 (1SR,2RS,6SR,8RS,12RS)-10-(3-chlorophenoxymethyl)-10-hydroxy-12-methoxy-5,9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 
• 130184-40-6 (2,2,2-Trichloro-acetyl)-carbamic acid (3aS,4R,5S,6aR)-4-[4-(3-chloro-phenoxy)-1-methoxy-3-oxo-butyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 

Relevant academic research and scientific papers

Intramolecular Acetalization of 5-Hydroxy Ketones and Enones. A Novel Transformation of Important Prostaglandin Intermediates under Acidic Conditions

Intermediates in the synthesis of ω-tetranor 16-aryloxy prostaglandins, which are 5-hydroxy enones undergo quantitative intramolecular transformation into cyclic methyl acetals in acidic methanolic solution.The reaction proceeds via the corresponding 5-hydroxy-3-methoxy ketones, which partly exist as hemiacetals.The structure of the compounds investigated was elucidated by 1H NMR spectroscopy and by X-ray analysis of the acetal (11).