62515-35-9

Basic information

• Product Name: (1SR,5RS,6RS,7RS)-6-<4-(3-Chlorophenoxy)-3-oxo-1(E)-butenyl>-7-trimethylsilyloxy-2-oxabicyclo<3.3.0>octan-3-one
• CAS NO: 62515-35-9
• Molecular Weight: 408.954
• Mol File: 62515-35-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1SR,5RS,6RS,7RS)-6-<4-(3-Chlorophenoxy)-3-oxo-1(E)-butenyl>-7-trimethylsilyloxy-2-oxabicyclo<3.3.0>octan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1SR,5RS,6RS,7RS)-6-<4-(3-Chlorophenoxy)-3-oxo-1(E)-butenyl>-7-trimethylsilyloxy-2-oxabicyclo<3.3.0>octan-3-one(62515-35-9)
• EPA Substance Registry System: (1SR,5RS,6RS,7RS)-6-<4-(3-Chlorophenoxy)-3-oxo-1(E)-butenyl>-7-trimethylsilyloxy-2-oxabicyclo<3.3.0>octan-3-one(62515-35-9)

Safety Data

• Hazardous Substances Data: 62515-35-9(Hazardous Substances Data)

Upstream product

• 40665-94-9 dimethyl 3-(3-chlorophenoxy)-2-oxopropylphosphonate 
• 91750-91-3 (1S^*,5R^*,6R^*,7R^*)-7-trimethylsilyloxy-3-oxo-2-oxabicyclo<3.3.0>octane-6-carbaldehyde 
• 90472-67-6 γ-lactone of 2β-trimethylsilyloxymethyl-3α-trimethylsilyloxy-5α-hydroxy-1α-cyclopentylacetic acid 
• 54423-47-1 (+/-)-(3aα,4α,5β,6aα)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopentafuran-2-one 

Downstream Products

• 53872-62-1 (3aS,4S,6aR)-4-[(E)-4-(3-Chloro-phenoxy)-3-oxo-but-1-enyl]-5-hydroxy-hexahydro-cyclopenta[b]furan-2-one 
• 130184-40-6 (2,2,2-Trichloro-acetyl)-carbamic acid (3aS,4R,5S,6aR)-4-[4-(3-chloro-phenoxy)-1-methoxy-3-oxo-butyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 129988-14-3 (1SR,2RS,6SR,8RS,12RS)-10-(3-chlorophenoxymethyl)-10-hydroxy-12-methoxy-5,9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 
• 130214-53-8 (1SR,2RS,6SR,8RS,12RS)10-(3-chlorophenoxymethyl)-10-hydroxy-12-methoxy-5.9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 
• 123989-25-3 (1SR,2RS,6SR,8RS)-10-(3-chlorophenoxymethyl)-10,12-dimethoxy-5,9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 
• 123989-25-3 (1SR,2RS,6SR,8RS,12RS)-10-(3-chlorophenoxymethyl)-10,12-dimethoxy-5,9-dioxatricyclo<6.4.0.0^2,6>dodecan-4-one 

Relevant articles and documents

A New Synthesis of an Important Prostaglandin Intermediate by Selective Oxidation of a Trimethylsilylated Primary Alcohol to the Corresponding Aldehyde

The bis(trimethylsilyl) ether of the prostaglandin precursor rac-3 was oxidized with high selectivity to the trimethylsilylated Corey aldehyde rac-1f using Collins reagent (chromium(VI) oxide/pyridine) in dichloromethane.This unstable compound was subjected without isolation to a twophase Horner olefination by adding the dimethyl phosphonate 4 and concentrated aqueous sodium hydroxide to the oxidation mixture.Thus, the prostaglandin intermediate rac-5 was obtained in a yield of 35-40percent in a convenient one-pot procedure.