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C24H26ClNO5 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1239897-03-0 Structure
  • Basic information

    1. Product Name: C24H26ClNO5
    2. Synonyms:
    3. CAS NO:1239897-03-0
    4. Molecular Formula:
    5. Molecular Weight: 443.927
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1239897-03-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C24H26ClNO5(CAS DataBase Reference)
    10. NIST Chemistry Reference: C24H26ClNO5(1239897-03-0)
    11. EPA Substance Registry System: C24H26ClNO5(1239897-03-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1239897-03-0(Hazardous Substances Data)

1239897-03-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1239897-03-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,9,8,9 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1239897-03:
(9*1)+(8*2)+(7*3)+(6*9)+(5*8)+(4*9)+(3*7)+(2*0)+(1*3)=200
200 % 10 = 0
So 1239897-03-0 is a valid CAS Registry Number.

1239897-03-0Downstream Products

1239897-03-0Relevant articles and documents

Bioinspired total synthesis and human proteasome inhibitory activity of (-)-salinosporamide A, (-)-homosalinosporamide A, and derivatives obtained via organonucleophile promoted bis-cyclizations

Nguyen, Henry,Ma, Gil,Gladysheva, Tatiana,Fremgen, Trisha,Romo, Daniel

, p. 2 - 12 (2011/03/23)

A full account of concise, enantioselective syntheses of the anticancer agent (-)-salinosporamide A and derivatives, including (-)-homosalinosporamide, that was inspired by biosynthetic considerations is described. The brevity of the synthetic strategy stems from a key bis-cyclization of a β-keto tertiary amide, which retains optical purity enabled by A1,3-strain rendering slow epimerization relative to the rate of bis-cyclization. Optimization studies of the key bis-cyclization, enabled through byproduct isolation and characterization, are described that ultimately allowed for a gram scale synthesis of a versatile bicyclic core structure with a high degree of stereoretention. An optimized procedure for zincate generation by the method of Knochel, generally useful for the synthesis of salino A derivatives, led to dramatic improvements in side-chain attachment and a novel diastereomer of salino A. The versatility of the described strategy is demonstrated by the synthesis of designed derivatives including (-)-homosalinosporamide A. Inhibition of the human 20S and 26S proteasome by these derivatives using an enzymatic assay are also reported. The described total synthesis of salino A raises interesting questions regarding how biosynthetic enzymes leading to the salinosporamides proceeding via optically active β-keto secondary amides, are able to maintain the stereochemical integrity at the labile C2 stereocenter or if a dynamic kinetic resolution is operative.

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