123992-30-3

Upstream product

• 123992-32-5 (3R,4S,5R,6S,7S,9R,10S,11S,12S,13S,14R)-4,6,10,12-Tetrakis-benzyloxy-14-ethyl-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one 
• 36019-62-2 2,3-Dihydro-3,5-dimethyl-4H-pyran-4-one (Pyrone 4) 
• 124095-53-0 Methyl 2,4-Dideoxy-2,4-dimethyl-α-L-xylopyranoside (Pyran 6) 
• 123992-05-2 cis/trans-(+/-)-5,6-Dihydro-2-methoxy-3,5-dimethyl-2H-pyran (Pyran 5) 
• 123992-07-4 2,4-Dideoxy-2,4-dimethyl-L-xylose Cyclic 1,3-Propanediyl Mercaptal (Diol 7) 
• 123992-08-5 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsolyl>-2,4-dimethyl-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Alcohol 8) 
• 123992-09-6 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2,4-dimethyl-3-O-(phenylmethyl)-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Dithiane 9) 
• 123992-11-0 1,5-Anhydro-2,4,6,8-tetradeoxy-9-O-<(1,1-dimethylethyl)-diphenylsilyl>-2,4,6,8-tetramethyl-7-O-(phenylmethyl)-L-glycero-D-gulo-non-1-en-3-ulose (Pyrone 11) 
• 123992-12-1 1,5-Anhydro-2,4,6,8-tetradeoxy-9-O-<(1,1-dimethylethyl)-diphenylsilyl>-2,4,6,8-tetramethyl-7-O-(phenylmethyl)-L-threo-L-galacto-non-1-enitol (Pyran 12) 
• 123992-13-2 <2S-<2α(2R*,3S*,4R*),3β,6β>>-<<4-<3,6-Dihydro-3,5-dimethyl-6-(1-methylethoxy)-2H-pyran-2-yl>-2-methyl-3-(phenylmethoxy)pentyl>oxy>(1,1-dimethylethyl)diphenylsilane (Pyran 13) 
• 123992-14-3 <2S-<2α(2R*,3S*,4R*),3β,5β,6β>>-(1,1-Dimethylethyl)<<2-methyl-3-(phenylmethoxy)-4-pentyl>oxy>diphenylsilane (Pyran 14) 
• 123992-15-4 <αS-<αR*(1S*,2S*,3R*),βR*,δS*>>-α-<4-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-1,3-dimethyl-2-(phenylmethoxy)-butyl>-β,δ-dimethyl-1,3-dithiane-2-butanol (Dithiane-Alcohol 15) 
• 123992-17-6 (2R,4S,5S,6R,7R,8S)-5,7-Bis-benzyloxy-9-(tert-butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-nonanal 
• 123992-16-5 <2S-(2R*,3S*,4S*,5R*,6R*,8S*)>-(1,1-Dimethylethyl)-<<8-(1,3-dithian-2-yl)-2,4,6-trimethyl-3,5-bis(phenylmethoxy)nonyl>oxy>diphenylsilane (Dithiane 16) 

Downstream Products

• 123992-29-0 <3R-(3R*,4S*,5S*,6S*,8R*,10S*,11S*,12R*,13R*,14S*)>-153-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-4,6,8,10,12,14-hexamethyl-5,7,11,13-tetrakis(phenylmethoxy)-3-pentadecanol (Alcohol 2) 
• 123992-33-6 <5R-(5R*,6R*,7R*,8S*,9S*,10R*,12S*,13S*,14R*,15R*,16S*)>-5-Ethyl-2,2,3,3,6,8,10,12,14,16,20,20-dodecamethyl-19,19-diphenyl-7,9,13,15-tetrakis(phenylmethoxy)-4,18-dioxa-3,19-disilaheneicosane (Protected Hexaol 41) 

Relevant academic research and scientific papers

Development of a fully synthetic stereoselective route to 6-Deoxyerythronolide B by reiterative applications of the Lewis acid catalyzed diene aldehyde cyclocondensation reaction: A remarkable instance of diastereofacial selectivity

The synthesis of racemic 2, which contains the relative stereochemistry appropriate to a synthesis of (9S)-dihydro-6-deoxyerythronolide B (see compound 38), is described. The synthesis features three Lewis acid catalyzed diene aldehyde cyclocondensation r