123994-72-9Relevant academic research and scientific papers
Interaction of GTP Derivatives with Cellular and Oncogenic ras-p21 Proteins
Noonan, Timothy,Brown, Neal,Dudycz, Lech,Wright, George
, p. 1302 - 1307 (2007/10/02)
A series of N2-substituted quanosine 5'-triphosphates was synthesized from the corresponding nucleosides.The nucleosides were prepared by treatment of N2-substituted guanines with tetra-O-acetylribose under conditions which maximized
Structure-Activity Relationships of N2-Substituted Guanines as Inhibitors of HSV1 and HSV2 Thymidine Kinases
Hildebrand, Catherine,Sandoli, Daniele,Focher, Federico,Gambino, Joseph,Ciarrocchi, Giovanni,et al.
, p. 203 - 206 (2007/10/02)
A series of N2-phenylguanines was synthesized and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2.Compounds with hydrophobic, electron-attracting groups in the meta position of the phenyl ring
