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2-[(4-chlorobenzyl)amino]-9H-purin-6-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

123994-85-4

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123994-85-4 Usage

Chemical Class

Synthetic purine analogue

Category

Chemotherapy drug

Subclass

Alkylating agent

Mechanism of Action

Interferes with the DNA structure of cancer cells, preventing their ability to replicate and causing their death

Potential Treatments

Acute myeloid leukemia, myelodysplastic syndromes, advanced solid tumors

Limitations

Significant toxicity, potentially severe side effects (e.g. myelosuppression, gastrointestinal disturbances)

Ongoing Research

Focused on optimizing therapeutic potential while minimizing adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 123994-85-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,9,9 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 123994-85:
(8*1)+(7*2)+(6*3)+(5*9)+(4*9)+(3*4)+(2*8)+(1*5)=154
154 % 10 = 4
So 123994-85-4 is a valid CAS Registry Number.

123994-85-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(4-chlorophenyl)methylamino]-3,7-dihydropurin-6-one

1.2 Other means of identification

Product number -
Other names 6H-Purin-6-one,2-[[(4-chlorophenyl)methyl]amino]-1,9-dihydro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123994-85-4 SDS

123994-85-4Downstream Products

123994-85-4Relevant academic research and scientific papers

Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)

-

Paragraph 0061-0062, (2014/10/16)

The present invention relates to a method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) and the use of the compounds in the prevention or treatment of disease, including pre-diabetes, type 2 diabetes, syndrome X, metabolic syndrome and obesity.

Structure-Activity Relationships of N2-Substituted Guanines as Inhibitors of HSV1 and HSV2 Thymidine Kinases

Hildebrand, Catherine,Sandoli, Daniele,Focher, Federico,Gambino, Joseph,Ciarrocchi, Giovanni,et al.

, p. 203 - 206 (2007/10/02)

A series of N2-phenylguanines was synthesized and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2.Compounds with hydrophobic, electron-attracting groups in the meta position of the phenyl ring

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