1240382-30-2Relevant academic research and scientific papers
Practical synthesis of quinoxalinones via palladium-catalyzed intramolecular N-arylations
Luo, Xuehong,Chenard, Etienne,Martens, Peter,Cheng, Yun-Xing,Tomaszewski, Mirosaw J.
, p. 3574 - 3577 (2010)
A practical and highly efficient route to the synthesis of pharmaceutically interesting quinoxalinone scaffolds is reported. The key step involves an intramolecular palladium-catalyzed N-arylation under microwave irradiation. The developed methodology tolerates a variety of bromoanilides to afford a diverse collection of bicyclic and polycyclic quinoxalinones in high yield.
