124052-01-3Relevant academic research and scientific papers
The photodegradation of quercetin: Relation to oxidation
Dall'Acqua, Stefano,Miolo, Giorgia,Innocenti, Gabbriella,Caffieri, Sergio
, p. 8898 - 8907 (2012)
The photostability of quercetin in alcoholic solutions was studied. Both UVA and UVB light induced degradation of quercetin, yielding a single product 1 deriving from oxidation and addition of an alcohol molecule to the 2,3 double bond. The same mechanism operated when quercetin was dissolved in alkaline solutions, and again a product 2 due to oxidation and addition of water was characterized. Comparison with quercetin analogs confirmed that, despite the presence of five hydroxy groups in quercetin, those in positions 3, 3', and 4' are mainly involved in the antioxidant activity of the compound , as well as in its photolability.
Mechanistic study on the enzymatic oxidation of flavonols
Ghidouche, Souhila,Es-Safi, Nour-Eddine,Ducrot, Paul-Henri
, p. 619 - 623 (2008/09/16)
Several flavonols have been transformed upon treatment by Trametes versicolor laccase. Most of the major oxidation products have been isolated by HPLC as pure compounds and their structures have been, when possible, investigated through spectral methods (HPLC-MS and NMR). The results are coherent with the predominance of a dismutation process, leading to cation formation, over direct radical-radical coupling.
