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4-Pyrimidineacetic acid ethyl ester is a chemical compound that plays a significant role in organic synthesis, particularly within the pharmaceutical and agrochemical industries. It is distinguished by the presence of a pyrimidine ring, a heterocyclic compound, along with an acetic acid and an ethyl ester group. This unique structure endows it with the ability to engage in a range of chemical reactions. 4-Pyrimidineacetic acid ethyl ester is represented by the chemical formula C9H12N2O2 and is typically found as a clear liquid. Despite its potential applications, it is not extensively studied, and as a result, detailed information regarding its properties and safety is somewhat limited.

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  • 1240606-58-9 Structure
  • Basic information

    1. Product Name: 4-Pyrimidineacetic acid ethyl ester
    2. Synonyms: 4-Pyrimidineacetic acid ethyl ester;ethyl 2-(pyriMidin-4-yl)acetate;Methyl 2-(pyriMidin-4-yl)acetate;PyriMidin-4-Yl-Acetic Acid Ethyl Ester
    3. CAS NO:1240606-58-9
    4. Molecular Formula: C8H10N2O2
    5. Molecular Weight: 166
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1240606-58-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 256℃
    3. Flash Point: 109℃
    4. Appearance: /
    5. Density: 1.144
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 1.44±0.10(Predicted)
    10. CAS DataBase Reference: 4-Pyrimidineacetic acid ethyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-Pyrimidineacetic acid ethyl ester(1240606-58-9)
    12. EPA Substance Registry System: 4-Pyrimidineacetic acid ethyl ester(1240606-58-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1240606-58-9(Hazardous Substances Data)

1240606-58-9 Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrimidineacetic acid ethyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Pyrimidineacetic acid ethyl ester is utilized as a building block for the creation of novel agrochemicals. Its versatility in chemical reactions enables the synthesis of compounds that can be used in crop protection, pest control, and other agricultural applications.
Used in Organic Synthesis:
4-Pyrimidineacetic acid ethyl ester is employed as a versatile reagent in organic synthesis. Its ability to participate in a variety of chemical reactions makes it a valuable tool for the preparation of complex organic molecules, which can be further utilized in various industries, including materials science and specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 1240606-58-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,0,6,0 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1240606-58:
(9*1)+(8*2)+(7*4)+(6*0)+(5*6)+(4*0)+(3*6)+(2*5)+(1*8)=119
119 % 10 = 9
So 1240606-58-9 is a valid CAS Registry Number.

1240606-58-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 2-(pyrimidin-4-yl)acetate

1.2 Other means of identification

Product number -
Other names ethyl 2-pyrimidin-4-ylacetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1240606-58-9 SDS

1240606-58-9Downstream Products

1240606-58-9Relevant articles and documents

Dual Gold/Silver Catalysis: Indolizines from 2-Substituted Pyridine Derivatives via a Tandem C(sp3)–H Alkynylation/Iminoauration

Han, Chunyu,Liu, Yaowen,Tian, Xianhai,Rominger, Frank,Hashmi, A. Stephen K.

supporting information, p. 9480 - 9484 (2021/12/17)

A dual gold/silver-catalyzed cascade C(sp3)–H alkynylation/iminoauration of 2-substituted pyridines with hypervalent iodine(III) reagents for the synthesis of indolizines is described. This novel reaction involves the formation of an alkynyl Au(III) species, a dual gold/silver-catalyzed C(sp3)–H functionalization, and a subsequent iminoauration process. A number of indolizines bearing diverse functionalities were prepared in good to excellent yield. Furthermore, a gram-scale reaction was efficiently conducted.

SWEET FLAVOR MODIFIER

-

Page/Page column 88; 89, (2014/03/21)

The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

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