1240642-73-2 Usage
General Description
5-Amino-6-bromo-1-naphthonitrile is a chemical compound with the molecular formula C10H6BrN3. It is a naphthalenylamine derivative that contains a bromine atom and a nitrile group. 5-aMino-6-broMo-1-naphthonitrile is commonly used as a building block in organic synthesis and medicinal chemistry. Its versatile reactivity and ability to participate in various chemical reactions make it a valuable intermediate for the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it has been studied for its potential biological activities and its role as a fluorescent probe in cell imaging and biochemical assays.
Check Digit Verification of cas no
The CAS Registry Mumber 1240642-73-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,0,6,4 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1240642-73:
(9*1)+(8*2)+(7*4)+(6*0)+(5*6)+(4*4)+(3*2)+(2*7)+(1*3)=122
122 % 10 = 2
So 1240642-73-2 is a valid CAS Registry Number.
1240642-73-2Relevant articles and documents
A highly selective low-background fluorescent imaging agent for nitric oxide
Yang, Youjun,Seidlits, Stephanie K.,Adams, Michelle M.,Lynch, Vincent M.,Schmidt, Christine E.,Anslyn, Eric V.,Shear, Jason B.
, p. 13114 - 13116 (2010)
We introduce a novel sensing mechanism for nitric oxide (NO) detection with a particular easily synthesized embodiment (NO550), which displays a rapid and linear response to NO with a red-shifted 1500-fold turn-on signal from a dark background. Excellent selectivity was observed against other reactive oxygen/nitrogen species, pH, and various substances that interfere with existing probes. NO550 crosses cell membranes but not nuclear membranes and is suitable for both intra-and extracellular NO quantifications. Good cytocompatibility was found during in vitro studies with two different cell lines. The high specificity, dark background, facile synthesis, and low pH dependence make NO550 a superior probe for NO detection when used as an imaging agent.
