124072-88-4

Usage

Uses

Used in Pharmaceutical Industry:
1(2H)-Pyridazinecarboxylic acid, tetrahydro-, phenylmethyl ester is used as an intermediate in the synthesis of various drugs for its ability to contribute to the formation of complex molecular structures. Its role in drug development is significant, as it can be a part of the process that leads to the creation of new and effective medications.
Used in Chemical Research:
In the field of chemical research, 1(2H)-Pyridazinecarboxylic acid, tetrahydro-, phenylmethyl ester is utilized as a key component in the development of new chemical processes. Its unique properties allow researchers to explore novel reactions and syntheses, potentially leading to the discovery of innovative materials and compounds.
Safety and Handling:
It is important to handle and store 1(2H)-Pyridazinecarboxylic acid, tetrahydro-, phenylmethyl ester with care due to its potential hazards, such as causing irritation to the skin and eyes. Only trained professionals should work with this chemical in a controlled laboratory setting to ensure safety and proper use.

Upstream product

• 501-53-1 benzyl chloroformate 
• 57699-88-4 1-tert-butoxycarbonyl-2-carbobenzyloxyhydrazine 
• 505-19-1 piperidazine 
• 154972-38-0 benzyl 2-(tert-butoxycarbonyl)hexahydropyridazine-1-carboxylate 

Downstream Products

• 648958-44-5 2-methoxyoxalyl-tetrahydro-pyridazine-1-carboxylic acid benzyl ester 
• 802982-87-2 5,6-dihydro-4H-pyridazine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis and conformational preferences in solution and crystalline states of an aza-tripeptide

The aza-tripeptide Boc-Ala-AzPip-Ala-NHiPr (AzPip: 2-aza pipecolyl residue) was synthesized in seven steps using preferentially the diisopropylcarbodiimide/1-hydroxy-7-aza-benzotriazole (DIPCDI/AtOH) coupling method and via the Boc-AzPip-OBzl pivotal inte

The synthesis, structure and reactivity of 1-thioxotetrahydropyridazino[1,2-α][1,2,4]triazin-4(1H)-one

The synthesis of 1-thioxotetrahydropyridazino[1,2-a][1,2,4]triazin-4-(1H)-one 3 in five steps from tert-butyl carbazate and its transformation into 3-benzylidene and 1-amino derivatives are described. Its crystal structure is presented showing it to be an

Formation of unnatural cyclic amino acid equivalent from the simple cyclic hydrazine

An alternative method for the synthesis of unnatural cyclic amino acid equivalent from the simple cyclic hydrazine via oxidation and cyanation was developed.

Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects

Nonimmunosuppressant ligands, exemplified by GPI 1046 (1), for the peptidyl-prolyl isomerase FKBP12 have been found to unexpectedly possess powerful neuroprotective and neuroregenerative effects in vitro and in vivo. We have extensively explored the thera